BIPOLAR DISORDER

This study tests a smartphone app designed to help people with bipolar disorder who also struggle with alcohol or drug use. Researchers at Mayo Clinic want to see if the app is easy to use and acceptable to patients, and whether it can reduce cravings and substance use. The study…

This pilot study will test whether a high-fat, low-carbohydrate (ketogenic) diet can help reduce symptoms of bipolar disorder in 100 adults living in rural Alabama. Participants will continue their usual treatments while adding the diet. The goal is to see if this affordable, foo…

This study tests whether empagliflozin, a medicine used for diabetes, can help reduce depression in people with bipolar disorder who also have insulin resistance. Insulin resistance is common in bipolar disorder and may worsen mood symptoms. The study will involve 20 adults over …

This study tests a group program designed to help veterans with serious mental illness feel more comfortable and confident working with their healthcare teams. The goal is to improve collaboration so that care better matches each veteran's personal goals. About 119 veterans from …

This study tests a new way to monitor muscle activity during electroconvulsive therapy (ECT) for depression, bipolar disorder, or schizophrenia. It compares a standard arm tourniquet with a newer method using a vein tourniquet and low-dose medication. The goal is to see which met…

This study looks at how mental state, emotional eating, and sleep quality together influence the risk of metabolic syndrome (a cluster of conditions like high blood pressure and blood sugar) in 78 adults with schizophrenia or bipolar disorder. Researchers will measure participant…

This study looks at how the brain handles stopping and ignoring distractions in people with bipolar disorder or major depression. Researchers will use brain scans and thinking tasks with emotional faces to find differences between the two conditions. The goal is to improve diagno…

This study is creating a large biobank in Turkey for people with bipolar disorder. Researchers will collect blood samples and detailed health information from 1,000 participants to study the genes and biology behind the condition. The goal is to improve diagnosis and treatment in…

This study looks at how brain networks relate to thinking and memory problems in people with schizophrenia, bipolar disorder, or major depression. Researchers will use brain scans and cognitive tests to build models that could help diagnose these conditions and predict treatment …