BIPOLAR DISORDER
Clinical trials for BIPOLAR DISORDER explained in plain language.
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New hope for tough depression: boosting a Fast-Acting drug with talk therapy
Disease control TerminatedThis study tested whether combining a fast-acting antidepressant nasal spray (esketamine) with a specific type of talk therapy (Behavioral Activation) works better than the spray alone for people with hard-to-treat depression. The goal was to see if the therapy, done while the dr…
Matched conditions: BIPOLAR DISORDER
Phase: NA • Sponsor: The Royal's Institute of Mental Health Research • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Study links mental health drugs to heart Risk—Tests solutions
Disease control TerminatedThis study looked at whether certain medications for schizophrenia and bipolar disorder increase the risk of heart disease. Researchers measured cholesterol levels and heart activity in 48 participants already taking these medications. They then tested whether changing medication…
Matched conditions: BIPOLAR DISORDER
Phase: PHASE3 • Sponsor: Northwestern University • Aim: Disease control
Last updated Apr 02, 2026 14:58 UTC
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Safety check for bipolar drug halted
Disease control TerminatedThis study aimed to check the long-term safety and side effects of an investigational drug called BHV-7000 for adults with bipolar I disorder. It was an extension study for 94 people who had already completed a previous short-term trial. The main goal was to monitor for any serio…
Matched conditions: BIPOLAR DISORDER
Phase: PHASE2 • Sponsor: Biohaven Therapeutics Ltd. • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New app aims to help veterans at risk of suicide by teaching them to recognize their feelings
Symptom relief TerminatedThis study tested a new program for veterans with serious mental illness who are at risk of suicide. The program combined weekly group education with a smartphone app designed to help people better recognize and understand their own emotions, a skill linked to lower suicide risk.…
Matched conditions: BIPOLAR DISORDER
Phase: PHASE1 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Apr 02, 2026 14:56 UTC
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Brain scans probe why some bipolar treatments fail
Knowledge-focused TerminatedThis study aimed to understand differences in brain wiring between people whose bipolar disorder responds to treatment and those for whom it does not. Researchers used MRI brain scans to compare these groups and healthy volunteers. The goal was to identify brain pathways that cou…
Matched conditions: BIPOLAR DISORDER
Sponsor: Jennifer Sweet • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:24 UTC