ASTHMA

This study tested an experimental drug called RPT193 in 38 adults with moderate-to-severe asthma that was not fully controlled by standard inhalers. The goal was to see if RPT193 could prevent asthma attacks and improve lung function. However, the trial was terminated early, mean…

This study tested an oral drug called dexpramipexole in over 1,000 people with severe eosinophilic asthma, a type of asthma linked to high levels of certain white blood cells. The goal was to see if the drug could reduce serious asthma attacks over 52 weeks when added to standard…

This study tested a daily pill called dexpramipexole in 654 people with severe eosinophilic asthma, a type of asthma linked to high levels of certain white blood cells. The goal was to see if the drug could reduce serious asthma attacks over 52 weeks. The trial was terminated ear…

This study tested an inhaled drug called ARO-MUC5AC in healthy people and those with asthma or COPD. The goal was to see if it was safe and could improve lung function by reducing mucus. The study was terminated early, so results are limited.

This study tested a chewable tablet called fevipiprant in children aged 6 to 12 with asthma. The goal was to measure how the drug moves through the body and check its safety. Only 11 children took part before the study was stopped early.

This study tested a 20% n-acetylcysteine (NAC) mist to help clear mucus in people with moderate-to-severe asthma. Participants received either NAC or a placebo for two weeks, then switched. The trial was stopped early after enrolling only 4 people, so no clear conclusions can be …

This study looked at what causes sudden, severe asthma attacks in adults aged 18 to 75. Researchers measured the thickness and stickiness of mucus from patients having an asthma attack to better understand the disease and how inhaled steroids work. The goal was to find new ways t…

This study looked at whether a specific gene (PDE4) affects how children with asthma respond to the rescue inhaler salbutamol. Researchers planned to compare lung function changes before and after the medication in children aged 6 to 18 with persistent asthma. The goal was to fin…

This study followed 152 children aged 3 to 5 years to see how being born early (before 37 weeks) affects lung function. Researchers measured breathing using special tests and checked for signs of asthma and allergies. The goal was to learn more, not to test a new treatment.

This study aimed to see if new CT scan methods could detect changes in bone density, structure, and marrow fat in people taking oral steroids for severe asthma. Researchers planned to compare steroid users to a control group, but the study was stopped early and only enrolled 2 pa…