ARTHROPLASTY, REPLACEMENT, KNEE

This study looked at how well a specific knee replacement system (the DePuy LCS Complete) works in people needing a new knee joint. It involved 241 adults with arthritis or similar conditions. The main goal was to check the system's performance during surgery and with X-rays, and…

This study tested whether an oral drug called Dimolegin is as safe and effective as standard heparin injections (Clexane) for preventing dangerous blood clots after hip or knee replacement. 215 adults undergoing elective joint replacement took either the pill or the injection. Th…

This study looked at whether showing people pictures of their worn-out knee cartilage and the new artificial joint during surgery helps them feel less pain and move better afterward. About 80 adults with severe knee arthritis who had a total knee replacement took part. The goal w…

This study tested whether giving lidocaine through an IV works as well as a numbing shot near the knee (nerve block) for pain after knee replacement. 120 adults having knee surgery were randomly assigned to one of the two methods. The main goal was to see how much opioid pain med…

This study tested whether ear acupoint therapy (a type of acupuncture on the ear) can help people recover better after total knee replacement surgery. 116 patients aged 50-80 took part. The therapy aimed to reduce pain, swelling, anxiety, and improve knee movement and scar healin…

This study tested whether a brief behavioral program called Acceptance and Commitment Therapy (ACT) could help at-risk veterans avoid persistent pain and disability after total knee replacement. About 400 veterans scheduled for knee surgery were randomly assigned to receive eithe…

This study looked at 60 adults having knee replacement surgery to compare two types of nerve blocks for pain relief. One group got a BiFeS block plus an adductor canal block, and the other got an IPACK block plus an adductor canal block. Researchers measured how much pain medicin…

This study looked at whether physical rehabilitation after hip or knee replacement surgery actually helps people function better in daily life. 169 adults who had surgery were randomly assigned to receive rehab or no rehab. The goal was to see if rehab makes a real difference in …

This study looked at 20 people with severe knee arthritis who needed knee replacement surgery. Half received a rotating platform implant and half a fixed platform implant. Researchers used 3D walking analysis before and after surgery to compare how well each implant restored natu…

This study looked at how to best dose tranexamic acid (TXA) during hip or knee replacement surgery to reduce blood loss and the need for transfusions. Researchers gave 21 adults either a standard dose or a lower dose if they had kidney problems, then measured drug levels in the b…