Arthroplasty, replacement, knee

This study tests whether a single surgery to replace an infected artificial knee works as well as the standard two-surgery approach. About 153 patients with a chronic knee infection will be randomly assigned to one of the two treatments. Researchers will track pain, function, and…

This study tests a new nerve block called BiFeS against the standard iPACK block for pain after knee replacement surgery. 88 adults having a knee replacement will be randomly assigned to receive one of the two blocks. The goal is to see which provides better pain relief and helps…

This study looks at using different amounts of steroids injected into the knee during total knee replacement surgery to control pain. Researchers want to find the safest and most effective dose to help patients recover faster and feel better. The trial involves 120 adults having …

This study tests whether nurse-led telehealth visits can detect complications and support recovery as well as in-person visits after total knee replacement. About 98 adults who had their first knee replacement will receive follow-up care either through a mobile app or at the clin…

This study will follow 220 adults having knee replacement surgery to see if a short burst of pain after a nerve block (called rebound pain) is linked to chronic pain that lasts for months. Participants will keep pain diaries and answer surveys at 3 and 6 months after surgery. No …

After knee replacement, a nerve block called the adductor canal block is often used to control pain while preserving leg strength. But it does not work equally well for everyone. This study will examine whether ultrasound measurements—such as tissue depth and nerve visibility—can…

This study is testing whether a special germ-fighting drape placed on the skin during hip or knee replacement surgery can reduce bacterial contamination. About 179 adults having a first-time hip or knee replacement will take part. Researchers will take samples from the surgical s…

This study adds a return-to-sports test to an existing knee replacement recovery study. The test uses a stepwise approach to assess athletic readiness, starting with low-level sports and progressing only if safe. Researchers hope to provide an objective way to guide patients back…