AORTIC VALVE STENOSIS
Clinical trials for AORTIC VALVE STENOSIS explained in plain language.
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New heart valves show promise for severe aortic stenosis in indian patients
Disease control CompletedThis study tested two new heart valves (Portico and Navitor) in 30 Indian patients with severe aortic stenosis who were at high risk for surgery. The goal was to see if the valves were safe and worked well. Researchers tracked complications, valve function, and quality of life fo…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 26, 2026 05:30 UTC
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New heart valve shows promise for aortic stenosis patients
Disease control CompletedThis study tested a new heart valve called Evolut PRO in 638 people with a narrowed or failing aortic valve. The valve was implanted through a tube in the artery, avoiding open-heart surgery. The main goal was to see how many patients survived 30 days after the procedure. The stu…
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: Medtronic Cardiovascular • Aim: Disease control
Last updated May 26, 2026 05:29 UTC
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New blood thinner combo tested for safer heart valve recovery
Disease control CompletedThis study tested whether a single blood thinner (ticagrelor) is safer than the standard two-drug combination (aspirin plus clopidogrel) after TAVI, a minimally invasive heart valve replacement for aortic stenosis. Researchers enrolled 50 older adults and tracked complications li…
Matched conditions: AORTIC VALVE STENOSIS
Phase: PHASE3 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated May 26, 2026 05:23 UTC
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New TAVI approach may skip risky step, improving heart valve replacement
Disease control CompletedThis study tested whether implanting a new aortic valve without first using a balloon to stretch the old valve is better than the standard approach. 250 patients with severe aortic stenosis who were too high-risk for open-heart surgery took part. The goal was to see if skipping t…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Disease control
Last updated May 26, 2026 04:38 UTC
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Can a common diabetes pill boost heart healing after valve surgery?
Disease control CompletedThis study tested whether empagliflozin, a drug usually used for diabetes, helps the heart recover better after aortic valve replacement. 206 adults with severe aortic stenosis took either the drug or a placebo for 6 months after their valve procedure. The main goal was to see if…
Matched conditions: AORTIC VALVE STENOSIS
Phase: PHASE4 • Sponsor: Rigshospitalet, Denmark • Aim: Disease control
Last updated May 26, 2026 04:34 UTC
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Nerve block eases pain during heart valve procedure, study finds
Symptom relief CompletedThis study tested whether an ultrasound-guided TAP block (a type of nerve block in the belly area) can reduce pain and improve stability during a minimally invasive heart valve replacement called TAVI. Fifty adults having elective TAVI took part. The goal was to see if the block …
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated May 26, 2026 05:25 UTC
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Nerve block eases pain during heart valve procedure, study finds
Symptom relief CompletedThis study tested whether a new type of nerve block, called PENG, can reduce pain and the need for strong painkillers in 40 adults undergoing a minimally invasive heart valve replacement (TAVI). The block is injected near the hip under ultrasound guidance. Researchers measured ho…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Medipol University • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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22 heart patients help uncover scarring clues before valve surgery
Knowledge-focused CompletedThis study involved 22 people with severe aortic stenosis who were about to have heart valve surgery. Before surgery, they had an ultrasound and a heart MRI, and during surgery a tiny heart tissue sample was taken. Researchers then looked back at the data to see if scarring in th…
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: Norwegian University of Science and Technology • Aim: Knowledge-focused
Last updated May 26, 2026 05:26 UTC
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Tiny vessel traffic during heart surgery: which machine method wins?
Knowledge-focused CompletedThis study looked at 60 heart surgery patients to see how blood flow in tiny blood vessels (microcirculation) differs between two types of heart-lung machines: a newer, less invasive one and a standard one. The goal was simply to observe and compare, not to treat a disease. Resul…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Aristotle University Of Thessaloniki • Aim: Knowledge-focused
Last updated May 26, 2026 05:26 UTC
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Heart stiffness measured during surgery: a new way to understand aortic stenosis?
Knowledge-focused CompletedThis study measured how stiff the heart muscle is in people having surgery for aortic stenosis (a narrowed heart valve) compared to those having bypass surgery. Researchers used a special ultrasound technique called elastography directly on the heart during the operation. The goa…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated May 26, 2026 04:38 UTC
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New program aims to cut wait times for Life-Saving heart valve procedure
Knowledge-focused CompletedThis study tested a program to reduce the time it takes for patients with aortic stenosis to get a TAVI procedure. The program included an e-health tool for patients and families, plus organizational changes at hospitals. Researchers measured how many patients received TAVI withi…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated May 26, 2026 04:36 UTC
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Computer alerts aim to close gap in heart valve care
Knowledge-focused CompletedThis study tested whether automated alerts sent to doctors through electronic health records could improve care for patients with severe aortic stenosis or mitral regurgitation. Over 2,100 patients were included, and the alerts highlighted those who might need a heart valve proce…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Tempus AI • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Heart imaging breakthrough may sharpen TAVI predictions
Knowledge-focused CompletedThis study tested whether two advanced heart ultrasound techniques (LACI and LV speckle tracking) can better predict complications like hospital readmission, heart attack, or stroke after TAVI valve replacement. Researchers studied 100 patients with severe aortic stenosis before …
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: Damanhour University • Aim: Knowledge-focused
Last updated May 18, 2026 12:12 UTC
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MRI scans reveal how heart heals after valve surgery
Knowledge-focused CompletedThis study looked at 86 adults with severe aortic valve stenosis who had valve replacement surgery. Researchers used heart MRI scans before and one year after surgery to measure scarring in the heart muscle. The goal was to see if the scarring improves after surgery and whether M…
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated May 18, 2026 12:04 UTC