AORTIC VALVE STENOSIS
Clinical trials for AORTIC VALVE STENOSIS explained in plain language.
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New electric slicing technique aims to unblock the heart
Disease control TerminatedThis study tested a new procedure called SESAME for people with a thickened heart wall that blocks blood flow. The goal was to see if doctors could safely use a wire to slice away extra tissue inside the heart. Only one person took part before the study was stopped early.
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated May 26, 2026 09:56 UTC
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Experimental valve treatment tested in just one patient
Disease control TerminatedThis study tested a device called Leaflex Performer for people with severe aortic stenosis who could not have standard valve replacement. Only one person took part before the study was stopped. The goal was to see if the device was safe and could improve valve function.
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Pi-cardia • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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Massive german study aims to unlock best heart valve treatments
Knowledge-focused TerminatedThis study is a large registry that followed 180,000 people in Germany with aortic valve problems (leaky or narrowed valves). It compared newer, less invasive treatments like TAVI with traditional open-heart surgery to see which works best and is safest. The goal was to help doct…
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: German Aortic Valve Registry • Aim: Knowledge-focused
Last updated May 26, 2026 09:55 UTC