ALCOHOL USE DISORDER (AUD)
Clinical trials for ALCOHOL USE DISORDER (AUD) explained in plain language.
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LSD shows promise in cutting heavy drinking days
Disease control Recruiting nowThis study tests whether two doses of LSD can help people with alcohol use disorder drink less heavily. 128 adults who have recently stopped drinking will receive either a low or moderate-to-high dose of LSD in a supervised setting. The main goal is to see if LSD reduces the numb…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Phase: PHASE2 • Sponsor: Felix Mueller • Aim: Disease control
Last updated May 01, 2026 15:43 UTC
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Could a diabetes drug curb alcohol cravings?
Disease control Recruiting nowThis study tests whether a weekly injection of tirzepatide, a drug used for diabetes, can help reduce cravings for alcohol in people with alcohol use disorder. Twenty adults will receive either the drug or a placebo for 4 weeks. The goal is to see if it lowers cue-induced craving…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 01, 2026 15:43 UTC
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App and pills: a new way to curb heavy drinking in veterans
Disease control Recruiting nowThis study looks at whether adding a smartphone app to standard medication can help Veterans with alcohol use disorder drink less heavily. About 330 Veterans from VA primary care will either get medication alone or medication plus the app. The goal is to see if the app makes it e…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated May 01, 2026 15:41 UTC
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Could a tiny tablet under the tongue curb drinking and PTSD anxiety?
Symptom relief Recruiting nowThis early-phase study tests whether a sublingual form of dexmedetomidine (BXCL501) is safe and shows promise for reducing alcohol use and PTSD symptoms in heavy drinkers. Ten adults aged 21–65 with both alcohol use disorder and PTSD will take the drug daily for 28 days while res…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Phase: PHASE1 • Sponsor: Pharmacotherapies for Alcohol and Substance Use Disorders Alliance • Aim: Symptom relief
Last updated Apr 30, 2026 15:49 UTC
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Could a common painkiller curb alcohol cravings?
Symptom relief Recruiting nowThis early-phase study tests whether diclofenac, an FDA-approved pain reliever, can help people with alcohol use disorder by changing brain chemistry. Researchers will give 24 adults either a placebo or one of three doses of diclofenac and measure its effects on craving, mood, an…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Phase: PHASE1 • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Apr 29, 2026 15:01 UTC
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Gut check: can kicking the habit rewire addiction recovery?
Knowledge-focused Recruiting nowThis study looks at 100 people with substance use disorders who want to quit smoking. Half will get a 6-week smoking cessation program, while the other half continues usual care. Researchers will test blood and stool samples to see how quitting affects gut bacteria and metabolism…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Phase: NA • Sponsor: Sigmund Freud PrivatUniversitat • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC
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Hong kong study tests calendar trick to uncover hidden mental health history
Knowledge-focused Recruiting nowThis study aims to see if using a life history calendar helps people recall past mental health issues more accurately. Researchers will ask 2,500 adults in Hong Kong about their mental health, with half using a calendar as a memory aid. The goal is to improve how we measure lifet…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:49 UTC
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Can a phone app curb substance use in young people?
Knowledge-focused Recruiting nowThis study is testing a smartphone app designed to help young people aged 14 to 35 with alcohol or cocaine use disorder strengthen their self-control. Participants will use the app for short training sessions over a month, plus booster sessions. The goal is to see if the app is e…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Phase: NA • Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC