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Could a diabetes drug curb heavy drinking in HIV patients?

NCT ID NCT07040592

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 28 times

Summary

This pilot study is testing whether semaglutide, a drug used for diabetes and weight loss, can help people with HIV reduce their alcohol use. Thirty participants will receive the drug along with support from a pharmacist and psychiatrist. The goal is to see if the approach is practical and acceptable, and whether it leads to less drinking.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atlanta VA Medical Center

    RECRUITING

    Decatur, Georgia, 30033, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

semaglutide

What this could lead to

If this works, it could point toward a new way to help people with HIV reduce heavy drinking using a medication already approved for diabetes and weight loss.

What could go wrong

This is a very small, early pilot study with only 30 participants. It is testing an off-label use, so results may not apply broadly, and side effects are possible.

Conditions

The condition(s) this trial relates to.

alcohol abuse HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.