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Could a tiny tablet ease both heavy drinking and PTSD?

NCT ID NCT06335407

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 34 times

Summary

This early-phase study tests whether a sublingual form of dexmedetomidine (BXCL501) is safe and shows promise for treating alcohol use disorder in people who also have PTSD. Ten heavy drinkers with PTSD will take the drug and be monitored for changes in blood pressure, anxiety, and PTSD symptoms over 28 days. The goal is to gather enough safety and early effectiveness data to plan larger trials.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • VA Connecticut Healthcare System

    RECRUITING

    West Haven, Connecticut, 06516, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

alcohol abuse Alcohol Drinking post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.