ACNE VULGARIS

This study tested a new medication called imsidolimab for people with moderate to severe acne. 123 participants received either the drug or a placebo to see if it reduced acne lesions on the face over 12 weeks. The goal was to find a safer or more effective treatment option for a…

This study looked at whether taking probiotics can reduce levels of a protein called LRG1, which is linked to acne inflammation. Fifty adults with mild to moderate acne took probiotics, and researchers measured changes in their blood and skin. The goal was to see if probiotics co…

This study tested the acne cream Winlevi in 10 people with darker skin tones (Fitzpatrick types IV, V, VI). The goal was to see how many achieved clear or almost clear skin after 16 weeks. Researchers wanted to fill a gap because most acne studies have not focused on skin of colo…

This study tested whether oral metformin, a common diabetes medication, can treat moderate to severe acne as effectively as the antibiotic doxycycline. 68 people with acne took either metformin twice daily or doxycycline once daily for 12 weeks. Researchers measured acne improvem…

This study tested whether adding a non-invasive ear acupressure technique to a standard acne cream (adapalene) improves acne more than the cream alone. Sixty-four people with mild to moderate acne took part. Researchers measured changes in acne severity and lesion counts over the…

This study tested a treatment called dextrose phonophoresis for people with mild to moderate acne. It uses ultrasound to push a sugar solution into the skin. 115 people aged 18 to 30 took part. The goal was to see if it reduces acne severity and number of pimples.

This study tested a combination of two acne treatments—Winlevi (a hormone-blocking cream) and adapalene gel—to see how well they work together in everyday use. Twenty people with acne vulgaris used both treatments for 16 weeks. The main goal was to see how many achieved clear or …

This study tested a new gel called IDP-126 against a standard acne treatment (Epiduo Forte) and a placebo gel. About 686 people aged 12 and older with moderate to severe acne took part. The goal was to see if the new gel reduces pimples and clears skin better than the existing tr…

This study tested whether a generic tretinoin gel works as well as the brand-name Retin-A Micro for treating acne. Over 1,000 people with mild to moderate acne used one of the gels or a placebo for several weeks. The goal was to see if the generic version reduces pimples and blac…

This early-stage study tested a new topical medicine (PF-07905428) for acne in 52 healthy volunteers and people with moderate to severe acne. The main goal was to check safety and how the body processes the drug. Participants applied the cream daily for 2 to 4 weeks and were moni…

This study tested a dapsone gel against a placebo gel in 100 adults with mild-to-moderate acne. Participants applied the gel once daily for 8 weeks. Researchers measured acne severity, redness, oiliness, and quality of life to see if the gel helps improve skin and confidence.

This study tested whether a facial moisturizer is gentle and effective for people with mild to moderate acne. 47 participants used the product for 4 weeks. Researchers checked skin dryness, redness, and overall appearance, and participants reported how their skin felt. The goal w…