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Acne breakthrough? ear acupressure boosts standard Gel's power

NCT ID NCT07348978

Symptom relief Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding ear acupressure to a standard acne gel (adapalene) helps clear pimples better than the gel alone. Researchers enrolled 64 people with mild to moderate acne and compared the combination to the gel-only group. The goal was to see if the combo reduced acne severity and lesion counts more effectively.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Auricular acupressure (ear acupressure) and adapalene 0.1% gel
What this could lead to
If it works, this could point toward a simple, non-invasive add-on treatment for mild to moderate acne.
What could go wrong
This is a small, completed study (64 people) with no phase designation. The results may not apply to everyone, and ear acupressure's effect may be small or due to placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

64 people

The number who actually took part.

Started

Nov 2024

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female patients aged 18 to 35 years. * Clinical diagnosis of mild to moderate acne vulgaris based on the Global Acne Grading System (GAGS). * Willingness to comply with the study protocol and attend all scheduled visits. * Provided written informed consent prior to participation. Exclusion Criteria: * Severe acne vulgaris requiring systemic treatment. * Use of systemic acne treatments (such as isotretinoin, antibiotics, or hormonal therapy) within the past 4 weeks. * Use of topical acne treatments within 2 weeks prior to enrollment. * Presence of other dermatological conditions that may interfere with evaluation. * Pregnancy or breastfeeding. * Known allergy or hypersensitivity to adapalene or components of the intervention.

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Conditions

The condition(s) this trial relates to.

acne Acne Vulgaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acne vulgaris

Contacts and locations

Locations

  • Le Van Thinh Hospital

    Ho Chi Minh City, Ho Chi Minh City, Vietnam

More trials for these conditions

Other studies related to the condition(s) this trial covers.