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Probiotics show promise for acne relief

NCT ID NCT07277075

Symptom relief Sponsor: Benha University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether taking probiotics can reduce a protein in the blood linked to acne inflammation. Researchers measured this protein in 50 adults with mild to moderate acne before and after probiotic treatment. The goal was to see if probiotics could help ease acne symptoms by lowering inflammation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

50 people

The number who actually took part.

Started

Oct 2024

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This case-control study was conducted on all participants enrolled from the Dermatology \& Andrology Outpatient Clinic at Benha University Hospital, Egypt, between October 2024 and September 2025.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years. * Both sexes. * Had not used systemic or topical acne therapy for at least two months or two weeks before the research, respectively. * Participants with clinically diagnosed mild to moderate acne vulgaris (AV) based on the Global Acne Grading System (GAGS) Exclusion Criteria: * Pregnancy. * Lactation. * History of hypersensitivity to probiotic components. * Smoking. * Presence of infections. * Autoimmune or malignant diseases. * Receiving any systemic therapy likely to affect the microbiome or inflammatory biomarkers.

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Conditions

The condition(s) this trial relates to.

acne Acne Vulgaris influenza

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acne vulgaris Influence Probiotic Serum leucine-rich alpha-2 glycoprotein 1

Contacts and locations

Locations

  • Benha University

    Banhā, Benha, 13518, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.