ACNE VULGARIS

This study tests a cream called 1% clascoterone on 692 people aged 12 and older with moderate to severe acne. Participants apply the cream or a placebo to their face twice daily for 12 weeks. The goal is to see if the cream safely reduces acne better than a placebo.

This study compares two topical gels—metronidazole and clindamycin—to treat moderate acne in adults aged 18 to 35. Sixty participants will apply the assigned gel twice daily for 12 weeks. The goal is to see which gel reduces acne severity more effectively, as measured by a standa…

This study tests a prescription gel called CABTREO in 100 children aged 9 to 11 with moderate to severe acne. The gel contains three medicines to fight acne bacteria, unclog pores, and reduce inflammation. Researchers will check for side effects and measure how well the gel clear…

This early-stage trial tests a new drug called HB0043 in 21 adults with moderate to severe facial acne. The drug targets two proteins linked to acne inflammation. The main goal is to see if it is safe and reduces acne lesions and severity scores compared to a placebo.

This study tests three gels for mild-to-moderate acne: a standard clindamycin-retinoid cream, the same cream plus dexamethasone, and a new gel made from stem cell secretions (secretome). 189 people aged 15-40 will use one of the gels for 8 weeks. Researchers will measure how much…

This study tests whether taking oral probiotics for 12 weeks can reduce acne lesions and lower inflammation in people with moderate acne. Researchers will compare probiotics to a placebo in 64 Pakistani participants aged 15-35. The goal is to find a safe, antibiotic-free way to m…

This study tests a new gel containing spironolactone (a hormone blocker) against a standard acne gel (adapalene) in 40 people with mild to moderate acne. Each person will apply one gel to one side of their face and the other gel to the other side, so the results can be compared d…

This study tests a new cream called KR230109 for people with mild to moderate facial acne. About 180 adults aged 18 to 40 will use the cream or a placebo for 12 weeks. The goal is to see if the cream safely reduces pimples and skin bumps better than a placebo.

This study will test whether a gel containing dutasteride can treat facial acne better than a standard gel that combines three drugs (clindamycin, benzoyl peroxide, and adapalene). About 50 adults with acne will use one gel on half their face and the other gel on the other half f…

This study looks at whether certain fat molecules (ceramides and sphingosine-1-phosphate) in the blood are different in people with acne compared to healthy people. Researchers will collect blood samples from 80 participants (40 with acne and 40 without) to measure these molecule…