Polycystic ovary syndrome

Researchers compare dapagliflozin, a diabetes drug, with metformin, the standard insulin-sensitizing treatment, in women with polycystic ovary syndrome. The trial enrolls 70 women aged 18 to 40 who have PCOS and infertility. Over the study, the team measures changes in follicle-s…

Researchers compare dapagliflozin, a diabetes drug, with metformin, the standard insulin-sensitizing treatment, in women with polycystic ovary syndrome (PCOS). The trial enrolls 60 women aged 18 to 40 who have PCOS and infertility. The main goal is to see how each drug affects fe…

This trial tests whether acupuncture can improve insulin resistance in women with polycystic ovary syndrome (PCOS). The study includes two phases: first, a small group of 20 women receives active acupuncture plus lifestyle advice to check safety and feasibility. Then, a larger ra…

This trial tests whether adding inositol or metformin to either a Mediterranean or low-carbohydrate diet improves insulin resistance in obese women with polycystic ovary syndrome (PCOS). About 90 to 102 participants will be randomly assigned to one of six groups and followed for …

This study investigates whether combining high-intensity interval training (HIIT) with intermittent fasting (14-hour fast, 10-hour eating window) can reduce insulin resistance in obese women with polycystic ovary syndrome (PCOS). Participants will follow a supervised exercise pro…

This trial investigates whether giving obese women with polycystic ovary syndrome (PCOS) a GLP-1 receptor agonist (a drug that helps control appetite and blood sugar) along with healthy lifestyle education for 12 weeks before starting fertility treatment can improve their chances…

This study investigates whether a supervised, adapted physical activity program can improve how the body burns fat during walking in women with overweight or obesity, both with and without polycystic ovary syndrome (PCOS). Researchers will compare changes in fat oxidation and oth…

This study compares myo-inositol alone versus myo-inositol plus alpha-lactalbumin in 82 women with PCOS who want to conceive. Over 12 weeks, researchers will track pregnancy rates, menstrual regularity, and metabolic changes. The goal is to see if adding alpha-lactalbumin improve…

This study compares two drugs—metformin and myo-inositol—for managing polycystic ovary syndrome (PCOS) in 60 women. Over 3 months, researchers will check if either drug helps restore regular menstrual cycles and improve hormone balance. The goal is to see which option works bette…

This study tests a 24-week dietary program for overweight or obese women with polycystic ovary syndrome (PCOS). The goal is to see if a carefully planned, calorie-controlled diet can improve menstrual regularity and metabolic health better than standard care. 160 women will parti…

This study looks at whether a low-calorie Mediterranean diet plus a synbiotic supplement (a mix of good bacteria and fiber) can improve body measurements, blood markers, and quality of life in overweight or obese women with PCOS. About 32 women will be randomly assigned to get ei…

This study looks at whether a light fasting diet combined with magnesium supplements can improve cholesterol levels, reduce inflammation, and lower oxidative stress in women with polycystic ovary syndrome (PCOS). Forty-six women will follow the diet and take either magnesium or a…

This study looks at whether limiting food intake to an 8-hour window each day (16:8 time-restricted feeding) can improve weight, blood sugar, and appetite-related hormones in women with polycystic ovary syndrome (PCOS). Forty-five women will be split into three groups: two PCOS g…

This trial tests whether a structured educational program, based on the Expanded Health Belief Model, can encourage female high school students to adopt behaviors that protect against polycystic ovary syndrome (PCOS). The program includes sessions on PCOS awareness, perceived ris…

This study tests whether an 8-week exercise program done through a digital platform can improve symptoms of polycystic ovary syndrome (PCOS) in women aged 18-40. Participants will be split into three groups: digital exercise, in-person exercise, or general physical activity advic…

This study tests a 5-day online Theta Healing program—including meditation, visualization, and self-compassion exercises—in 142 women with PCOS. The goal is to see if it reduces fertility anxiety and improves body image compared to usual care alone. Results will be measured 6 wee…

This study will test if a mobile app that gives personalized Mediterranean diet advice can help women with PCOS improve their cholesterol, weight, and overall health. Sixty women will be split into two groups: one using the app and one getting standard lifestyle advice. The goal …

This study tests whether a daily berberine supplement (550 mg) can improve PCOS symptoms like excess hair growth, acne, and weight in 150 women aged 18-40. Participants are split into three groups: those not taking inositol, those already on inositol, and a control group receivin…

This study compares in vitro maturation (IVM) to conventional ovarian stimulation in 84 women with severe PCOS undergoing their first fertility treatment. The goal is to see which method causes less pain, fewer side effects, and better quality of life. Participants will fill out …

This study tests whether wet cupping (Hijama) can improve menstrual regularity, reduce pain, and boost fertility in women with PCOS. Sixty women aged 20-40 will be randomly assigned to receive three monthly cupping sessions or standard lifestyle advice. Researchers will track cha…

This study explores whether polycystic ovary syndrome (PCOS) independently contributes to fatty liver disease in adolescent girls, beyond the effects of obesity. Researchers will compare three groups of girls aged 10–18: those with PCOS and obesity, those with obesity alone, and …

This study looks at whether a hormone called preptin, which is released alongside insulin, is linked to insulin resistance in women with polycystic ovary syndrome (PCOS). Researchers will measure preptin levels in 60 women diagnosed with PCOS and compare them to markers of insuli…

This study investigates how the bodies of women with Polycystic Ovary Syndrome (PCOS) respond to sugar compared to women without the condition. Participants drink a sugary solution, and blood and urine samples are analyzed using advanced technology to track changes in proteins, m…

This study will follow 473 women with polycystic ovary syndrome (PCOS) and a control group to understand what affects their ability to get pregnant. Researchers will look at medical history, hormone levels, and lifestyle factors to see which ones help or hinder natural or assiste…

This observational study will collect existing lab results and medical history from 100 women aged 18 to 45 with PCOS. No treatments or interventions are given. The goal is to identify distinct hormonal and metabolic patterns that could help explain the condition and guide future…

This study looks at whether fertility treatments change irritable bowel syndrome (IBS) symptoms in women. Researchers will follow 120 women—60 with PCOS starting IVF and 60 freezing eggs for social reasons. Participants fill out questionnaires about gut symptoms, anxiety, and dep…

This study will measure levels of two proteins, SCUBE-1 and SCUBE-3, in the blood of women with polycystic ovary syndrome (PCOS) and compare them to healthy women. Researchers want to see if these proteins are linked to inflammation and a higher risk of heart problems. About 56 w…

This study compares two common ovarian stimulation protocols—PPOS (using a progesterone-like drug) and GnRH antagonist—in women with polycystic ovary syndrome (PCOS) who are undergoing preimplantation genetic testing (PGT-A). The goal is to see which method results in more geneti…

This study will check how often fibromyalgia occurs in women with polycystic ovary syndrome (PCOS) and how pain relates to mood and insulin resistance. About 140 women aged 18-40 with PCOS and a healthy control group will answer questionnaires and have pain thresholds measured. T…