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Could a simple diet and magnesium help women with PCOS?
NCT ID NCT07322120
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a light fasting diet combined with magnesium supplements can improve cholesterol levels, reduce inflammation, and lower oxidative stress in women with polycystic ovary syndrome (PCOS). Forty-six women will follow the diet and take either magnesium or a placebo for two months. Researchers will measure changes in blood fats and markers of inflammation before and after the treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- light fasting diet and magnesium supplements
- What this could lead to
- If it works, this could point toward a simple, low-cost way to improve heart health and reduce inflammation in women with PCOS.
- What could go wrong
- This is a small, early-stage trial with only 46 participants, so results may not apply to everyone. The diet and supplement may not produce meaningful changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 46 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. People between the ages of 19 and 65 2. People with a body mass index (BMI) ≤ 25 3. Diagnosis of polycystic ovary syndrome by a specialist based on the Rotterdam criteria Exclusion Criteria: 1. Failure of the participant to cooperate during the study 2. Use of drug therapy that affects carbohydrate or fat metabolism (including oral contraceptives, insulin sensitizers, antiepileptic drugs, antipsychotics, statins, and fish oil) within the past 6 months. 3. Planning for pregnancy, pregnant, or breastfeeding 4. In the perimenopausal stage 5. Low blood pressure 6. Presence of other diseases (such as congenital adrenal hyperplasia, Cushing's syndrome, androgen-secreting tumors, hyperprolactinemia, diabetes, thyroid disease, severe cardiovascular, gastrointestinal, renal, and hepatic diseases) 7. Performing high-intensity exercise
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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