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Ancient hijama therapy tested for PCOS relief

NCT ID NCT07169292

Symptom relief Sponsor: Princess Nourah Bint Abdulrahman University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether wet cupping (Hijama) can improve menstrual regularity, reduce pain, and boost fertility in women with PCOS. Sixty women aged 20-40 will be randomly assigned to receive three monthly cupping sessions or standard lifestyle advice. Researchers will track changes in cycle length, bleeding, pain, and pregnancy rates over 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
wet cupping (Hijama) therapy
What this could lead to
If it works, this could offer a non-drug option to help regulate periods and reduce pain in women with PCOS.
What could go wrong
This is a small, early-stage trial with only 60 participants. The results may not apply to everyone, and the procedure carries minor risks like bruising or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Female participants. * Aged 20 to 40 years. * Diagnosed with Polycystic Ovary Syndrome (PCOS) according to the Rotterdam criteria. * Willing to participate in the study and provide informed consent. * Not using any of the following in the last month: (Hormonal medications for menstruation, Herbal menstrual remedies or Metformin). Exclusion Criteria * Known diagnosis of uncontrolled thyroid dysfunction. * Diagnosis of diabetes mellitus. * Elevated FSH levels above 20 mIU/mL. * Hyperprolactinemia with serum levels above 1000 mIU/L. * Pregnant or lactating women. * Known coagulation disorders. * Anemia with hemoglobin levels less than 10 g/dL. * History of undergoing dry cupping, wet cupping, or acupuncture in the past 6 months. * History of surgical removal of both ovaries or the uterus. * Other causes of hyperandrogenism, including: * Late-onset non-classic 21-hydroxylase deficiency (excluded clinically; lab investigation if clinically indicated). * Ovarian androgen-secreting tumors. * Use of anabolic or androgenic drugs. * Cushing's syndrome. * Hypothalamic or pituitary disorders causing amenorrhea. * Primary ovarian insufficiency.

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Conditions

The condition(s) this trial relates to.

polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Polycystic ovarian syndrome (PCOS)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • King Abdullah bin Abdulaziz University Hospital

    Riyadh, Central, 13249, Saudi Arabia

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