Physiological sexual disorder

This trial tests whether injecting platelet-rich plasma (PRP) — a concentrate made from a person's own blood — into the penile plaque can reduce curvature and ease symptoms in men with Peyronie's disease. Half the participants receive PRP injections and half receive a placebo (sa…

This trial examines whether pelvic floor muscle exercises can improve vaginal and sexual health in postmenopausal women. Twenty women who are sexually active and have gone through menopause join the study. One group receives training from a physiotherapist and does home exercises…

This study tested whether adding a magnetic chair (extracorporeal magnetic innervation) to standard pelvic floor exercises helps men with premature ejaculation more than exercises alone. Forty-one men aged 25-45 took part over 8 weeks. Researchers measured pelvic floor muscle mov…

This study tests whether a 16-week digital pelvic floor rehabilitation program is feasible for women who have been treated for cervical cancer within the past five years. The program includes supervised group exercise sessions and home exercises, along with information on dilator…

This study tests whether a non-ablative radiofrequency treatment can improve vaginal tissue health and reduce symptoms of Genitourinary Syndrome of Menopause (GSM), such as dryness and discomfort, in postmenopausal women. Participants will be randomly assigned to receive either t…

This phase 2 trial tested whether estetrol (E4), a hormone pill, can help postmenopausal women with female sexual arousal disorder. 82 women took either estetrol or a placebo for 12 weeks. Researchers measured changes in sexual arousal and distress to see if the drug works better…

This study tested a treatment called percutaneous tibial nerve stimulation (PTNS) for women with sexual dysfunction. 79 women received either real PTNS or a fake version to see if it improved their sexual function. The goal was to find a non-drug option for this common problem.

This study tested whether one-on-one sessions with a trained nurse could help people with resistant hypertension better handle side effects like sexual problems and bladder control issues caused by their blood pressure medications. The goal was to see if this education helps pati…

This study tested a behavioral program called AWARE for college women aged 18-24 who have experienced sexual trauma and drink heavily. The program includes individual and group sessions to reduce alcohol use, sexual distress, and risk of future assault. Researchers followed 86 pa…

This study looked at whether using a vaginal dilator for 12 weeks helps women who had brachytherapy for cervical cancer. Researchers measured sexual function, self-compassion, and quality of life in 80 participants at three time points. The goal was to see if this simple tool can…

This study tested a program to help stem cell transplant survivors who have sexual problems. Participants met with a nurse for three months and got educational materials. The goal was to see if this improved their sexual satisfaction, quality of life, and mood. The study involved…

This study tested whether specialized sexual nursing care could help stroke patients and their partners manage sexual difficulties. Thirty stroke survivors and their partners were split into two groups: one received personalized counseling and education from trained nurses, while…

This study looked at whether a 10-week pelvic physical therapy program is practical for gynecologic cancer survivors who have sexual problems. Twenty survivors were enrolled to see if they could stick with the program and if it improved their sexual function and quality of life. …

This study tested whether injecting Botox into the penis and a nearby pelvic muscle can help men with lifelong premature ejaculation last longer during sex. 150 men were randomly assigned to receive either Botox or a placebo injection. The researchers measured ejaculation time an…

This study followed 317 men who used a digital health app (Kranus EDERA) for erectile dysfunction to see if their improvements lasted. Participants completed questionnaires about erectile function, overall health, and quality of life up to 3 months after finishing the 12-week app…

This study tested a new treatment for female sexual dysfunction using the women's own stem cells. Fifty women aged 40-50 received stem cell infusions or served as a control group. The goal was to see if the therapy safely improves sexual function and quality of life. Results are …

This study tested an online nurse-led program to help young women who had breast cancer improve their sexual health, body image, and menopausal symptoms. 43 women who finished treatment within the last five years took part in eight weekly sessions. The program aimed to see if it …

This study tested a 4-week online mindful compassion program for women who had finished cancer treatment and were in hospice care at home. The goal was to see if it could improve sexual function, well-being, and quality of life. Twenty-two women took part, and the program include…

This early-stage study tested a new mind-body program designed to help female survivors of colorectal and anal cancer improve their sexual well-being. Six women who had finished initial cancer treatment took part in group sessions. The main goal was to see if the program was acce…

This study aimed to develop and test two new questionnaires for people with recurrent urinary tract infections (UTIs). The Recurrent UTI Symptom Scale measures symptom severity, while the Recurrent UTI Impact Questionnaire looks at how the condition affects daily life, work, and …

This study followed up with 69 women who had pelvic pain for over 6 months to see if a special pain education class still helped them 5 years later. The women filled out questionnaires about their pain, daily life, and sexual function. The goal was to find out if the benefits of …

This study surveyed 385 women aged 35 or younger with early-stage breast cancer to learn their attitudes about the risk of infertility from adjuvant therapy. The goal was to understand how concerns about having children might influence their treatment choices. The results could h…

This completed observational study investigated sexual dysfunction in women with anorexia nervosa, comparing them to healthy women. Researchers used questionnaires to measure sexual function and eating disorder symptoms. The goal was to understand how anorexia may affect sexual h…

This completed study examined the link between erectile dysfunction, nerve pain, disease activity, and daily function in 90 men with axial spondyloarthritis (a type of arthritis affecting the spine). Participants were either on anti-TNF drugs, NSAIDs, or were healthy volunteers. …

This study tested whether an educational video series about sexual health is acceptable and useful for women undergoing breast cancer treatment. 32 women with early-stage breast cancer watched the videos over six months. Researchers measured how well the videos were received and …

This study looked at sexual problems in 553 adults with lung cancer. Researchers wanted to find out how common these issues are and how severe they can be. The goal is to help doctors better support patients during and after cancer treatment.

This study translated a detailed questionnaire about male sexual function into French and tested it with 14 men who have sexual dysfunction. The goal was to see if the questions were clear and easy to understand. This is a first step toward having a reliable tool for French-speak…

This study looked at how bladder cancer surgery (cystectomy) affects patients' sexual quality of life over time. Researchers gave 50 participants questionnaires before and 8 months after surgery to track changes. The goal is to better understand long-term effects that are often o…

This study looked at how much women in Turkey know about their pelvic floor muscles and Kegel exercises. Researchers surveyed 182 women who were sexually active and over 18. They measured knowledge, sexual function, and quality of life to understand awareness levels and identify …

This small study tested whether mild nerve stimulation could increase vaginal blood flow in women with sexual problems, spinal cord injury, or no issues at all. Nine women had a small sensor placed in the vagina to measure blood flow changes during stimulation. The goal was to un…

This study looked at whether ospemifene, a non-hormonal drug for vaginal dryness, also affects brain activity in postmenopausal women with sexual interest-arousal disorder. Twenty-five women took the drug or a placebo and underwent brain scans while watching sexual videos or smel…