Sexual health in arthritis patients under the microscope
NCT ID NCT07453628
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study examined the link between erectile dysfunction, nerve pain, disease activity, and daily function in 90 men with axial spondyloarthritis (a type of arthritis affecting the spine). Participants were either on anti-TNF drugs, NSAIDs, or were healthy volunteers. Researchers used questionnaires to measure sexual function and pain, aiming to see if these factors are connected.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If the findings are clear, this could help doctors better understand and address sexual health issues in men with this type of arthritis.
- What could go wrong
- This is a small, completed observational study, so it cannot prove cause and effect. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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90 people
The number who actually took part.
- Started
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Feb 2021
- Finished
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Jul 2021
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of male patients with ankylosing spondylitis followed at a tertiary university hospital outpatient clinic and age-matched healthy male volunteers. Patients are grouped according to ongoing treatment (anti-TNF therapy or NSAIDs). Healthy controls are recruited from hospital staff relatives. All participants are adults able to provide informed consent and complete validated questionnaires.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Male participants aged 18 years or older Diagnosis of ankylosing spondylitis according to accepted classification criteria (for patient groups) Receiving anti-TNF therapy or NSAIDs for at least 3 months (for patient groups) Ability to understand and complete study questionnaires Provided written informed consent For healthy control group: Male volunteers aged 18 years or older No history of inflammatory rheumatic disease Exclusion Criteria: Age under 18 years Use of anti-TNF therapy or NSAIDs for less than 3 months History of neurological disorders affecting sexual function Known severe psychiatric illness Use of medications known to significantly affect sexual function (e.g., antidepressants, antipsychotics) Refusal to participate or incomplete questionnaire data
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Uludag University Faculty of Medicine
Bursa, 16059, Turkey (Türkiye)
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