Botox shots to the penis may help men last longer in bed
NCT ID NCT07426640
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether injecting Botox into the penis and a nearby pelvic muscle can help men with lifelong premature ejaculation last longer during sex. 150 men were randomly assigned to receive either Botox or a placebo injection. The researchers measured ejaculation time and sexual satisfaction over six months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- botulinum toxin type A (Botox)
- What this could lead to
- If it works, this could offer a new treatment option for men with lifelong premature ejaculation who do not respond to standard therapies.
- What could go wrong
- This is a small, completed trial with 150 participants. The results may not apply to all men, and there are risks like injection site pain or temporary muscle weakness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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150 people
The number who actually took part.
- Started
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Nov 2021
- Finished
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Nov 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 50 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: male participants aged 20 years or older . diagnosis with lifelong premature ejaculation, in a stable heterosexual relationship for at least 6 months prior to enrollment, engaged in vaginal intercourse during the study period, willing and able to provide written informed consent - Exclusion Criteria: presence of acquired premature ejaculation, history of erectile dysfunction require treatment , current use of medication known to affect ejaculation or sexual function ,previous treatment with botulinum toxin for sexual dysfunction ,history of sever neurological or psychatricor endocrine disorders affection sexual function , active genital infection or penile anatomical abnormalities , hypersensitivity to botulinum toxin ,mythenia gravis \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Urology Al Mouwasat Hospital Riyadh
Riyadh, Riyadh Region, 11536, Saudi Arabia
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Other studies related to the condition(s) this trial covers.