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Botox shots to the penis may help men last longer in bed

NCT ID NCT07426640

First seen Feb 28, 2026 · Last updated Jun 23, 2026 · Updated 21 times

Summary

This study tested whether injecting Botox into the penis and a nearby pelvic muscle can help men with lifelong premature ejaculation last longer during sex. 150 men were randomly assigned to receive either Botox or a placebo injection. The researchers measured ejaculation time and sexual satisfaction over six months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Department of Urology Al Mouwasat Hospital Riyadh

    Riyadh, Riyadh Region, 11536, Saudi Arabia

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

botulinum toxin type A (Botox)

What this could lead to

If it works, this could offer a new treatment option for men with lifelong premature ejaculation who do not respond to standard therapies.

What could go wrong

This is a small, completed trial with 150 participants. The results may not apply to all men, and there are risks like injection site pain or temporary muscle weakness.

Conditions

The condition(s) this trial relates to.

physiological sexual disorder Premature Birth premature ejaculation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.