App-Based therapy for erectile dysfunction shows promise for lasting results
NCT ID NCT06501144
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study followed 317 men who used a digital health app (Kranus EDERA) for erectile dysfunction to see if their improvements lasted. Participants completed questionnaires about erectile function, overall health, and quality of life up to 3 months after finishing the 12-week app program. The app combines exercise, pelvic floor training, psychological support, and education.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- digital health application (Kranus EDERA) combining cardiovascular training, pelvic floor exercises, psychological support, and educational content
- What this could lead to
- If successful, this could show that a digital app can help men maintain long-term improvement in erectile function without ongoing medication.
- What could go wrong
- This is an observational follow-up study, not a controlled trial, so results may be influenced by other factors. It only includes men who already improved with the app, so it may not apply to everyone.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
-
317 people
The number who actually took part.
- Started
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Aug 2024
- Finished
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Sep 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study will include adults with erectile dysfunction who have started the 3-month therapy with the app-based therapeutic within the last 6 months
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men with erectile dysfunction of organic origin (ICD 10 code N48.4) and IIEF-5 score \< 21 as determined at therapy start with Kranus EDERA * Completion of the 12-week app-based therapy with Kranus EDERA * Improvement in the IIEF-5 score of ≥ 3 points after completion of the Kranus EDERA therapy compared to the score at the start of the therapy * Age over 18 Exclusion Criteria: * Failure to provide informed consent * Started a new therapy with Kranus EDERA between the end of the last therapy cycle and patient survey * Started PDE-5 inhibitor treatment during the Kranus EDERA therapy or between the end of the last therapy cycle and patient survey * Underwent prostatectomy (removal of the prostate gland), radiation or seeds of the prostate gland during the Kranus EDERA therapy or between the end of the last therapy cycle and patient survey * Performed auto-injection therapy (SKAT, MUSE) during the Kranus EDERA therapy or between the end of the last therapy cycle and patient survey * Obtained a penile implant during the Kranus EDERA therapy or between the end of the last therapy cycle and patient survey * Underwent major surgery in the small pelvis with probable impairment of the neurovascular supply (e.g., rectum resection, urinary bladder removal) during the Kranus EDERA therapy or between the end of the last therapy cycle and patient survey * Nervous diseases (e.g., multiple sclerosis (MS), Parkinson's disease, stroke, dementia, psychiatric diseases) acquired during the Kranus EDERA therapy or between the end of the last therapy cycle and patient survey * Developed pronounced circulatory disorders (peripheral arterial occlusive disease) during the Kranus EDERA therapy or between the end of the last therapy cycle and patient survey * Trauma involving the pelvis/penis/spine during the Kranus EDERA therapy or between the end of the last therapy cycle and patient survey * Any other newly developed diseases potentially affecting erectile function (e.g., leading to a longer period of hospitalization) during the Kranus EDERA therapy or between the end of the therapy cycle and patient survey
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CeRa Münster, Centre of Reproductive Medicine and Andrology
Münster, Germany, 48149, Germany
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