Osteoarthritis, hip

This early study is testing a new device called the ReNew Hip Implant in 15 people aged 14 to 64 with hip cartilage damage from conditions like osteoarthritis or hip impingement. The implant is surgically placed to repair the cartilage. Researchers are checking if it is safe and …

This trial tests whether using a navigation system during hip replacement surgery leads to more accurate joint reconstruction than the traditional measured technique. Researchers will compare the surgeon's pre-operative 3-D plan with the actual post-operative result in 100 patien…

This study is testing a new hip implant called the OR3O Dual Mobility System in 177 people who need hip replacement surgery. The goal is to see if the implant is safe and lasts longer without needing another surgery. Researchers will follow participants for up to 10 years to chec…

This study compares two treatments for end-stage hip osteoarthritis: total hip replacement surgery and progressive resistance training (strength exercises). About 109 adults aged 50 and older with severe hip arthritis will be randomly assigned to one of the two treatments. The ma…

This study compares three ways of delivering care for people with hip or knee osteoarthritis: a smartphone app with personalized exercises and education, a web-based exercise program, and standard group-based care. The goal is to see which approach best improves patients' ability…

This trial tests whether adding screws to secure the cup part of a hip replacement makes a difference in how well the implant stays in place. Participants aged 65-80 with hip osteoarthritis will receive a hybrid hip replacement, and half will get screws while the other half won't…

This study is testing a new type of hip resurfacing device made entirely of ceramic, designed for people with hip osteoarthritis, necrosis, or dysplasia. The goal is to see if it is as safe and effective as existing metal-on-metal devices, but without releasing metal ions into th…

This trial is testing two different cup designs for total hip replacement, both paired with the same stem, to see which one gives patients better hip function and less pain. About 120 people with hip arthritis or related conditions will be randomly assigned to receive either the …

This study follows 300 people who receive a hip replacement using either the Vivacit-E or Longevity liner, both made of a special plastic designed to last longer. The goal is to see how well these liners hold up over time, measuring how many are still in place without needing rep…

This study looks at how well the Insignia Hip Stem works and how safe it is for people needing a total hip replacement. It includes 313 adults with conditions like hip arthritis or fractures. Researchers will check implant survival and hip function for up to 10 years after surger…

This study planned to test a hip implant called the Restoration Anatomic Acetabular Shell in people needing revision surgery after a previous hip replacement failed. The goal was to see how well the implant holds up over time. However, the study was withdrawn before enrolling any…

This trial tests a new hip resurfacing system in 238 adults with hip osteoarthritis or mild dysplasia. The device is designed to cap the damaged joint rather than replace the entire hip. Researchers will compare pain, function, and safety to standard total hip replacement over tw…

This study is checking how well a new hip replacement part (the HYPE stem) works and lasts over 10 years. About 180 people with hip disease from arthritis or injury will get the implant. Doctors will use X-rays and surveys to see if the implant stays firmly in place and helps red…

This study planned to test a new hip replacement device (the HYPE stem) in people with hip arthritis or other hip damage. The goal was to see how well the device works and if it is safe. However, the study was withdrawn before any participants were enrolled, so no results are ava…

This study follows 52 people who already received a Vivacit-E hip liner during total hip replacement. Researchers will track how long the implant lasts and any problems over 10 years. The goal is to confirm the liner is safe and helps reduce pain and improve movement for conditio…

This study followed 413 people with hip arthritis who received a new type of hip replacement called the OXINIUM DH system. The goal was to see how well the implant worked and how safe it was over 10 years. Researchers checked pain, movement, and whether the implant stayed in plac…

This study is checking the long-term safety and performance of two hip implant devices (RingLoc Bipolar Acetabular Cup and Endo II Femoral Head) used in hip replacement surgery. Researchers will follow 116 patients who had their surgery at least eight years ago, tracking complica…

This study looks at the safety and performance of a cemented hip stem (TrendHip®) in 119 people who had hip replacement surgery. It tracks pain, function, and quality of life for up to 5 years after surgery. The goal is to confirm the device works well in everyday use.

This study follows 102 people who received the aneXys hip replacement cup to see how safe and effective it is over 2 years. Researchers measure if the cup moves and track pain and function using standard scores. The goal is to confirm the device works well in everyday use.

This study tests a new coating on a hip replacement implant that may help prevent infections and help the implant bond better with the bone. About 340 adults needing a hip replacement will receive either the coated or standard implant. The goal is to see if the coated implant wor…

This study tracks 100 adults who need a hip replacement to see how well the Avenir cemented hip stem works and holds up over time. Participants have conditions like arthritis, hip fractures, or hip damage from past surgeries. The main goal is to measure how long the implant lasts…

This study is testing a shoulder replacement device called the Medacta Shoulder System in 100 people with shoulder arthritis or rotator cuff tears. The goal is to see how well the implant works after 2 years, focusing on shoulder function, safety, and patient satisfaction. Partic…

This study compares two types of hip implant liners—one with vitamin E and one without—to see which lasts longer and causes fewer problems like wear or bone damage. Researchers are following 400 adults aged 18 to 75 who need a hip replacement due to arthritis. The goal is to find…

This study is following 202 people who received a special hip liner during hip replacement surgery. The goal is to see how long the liner lasts and whether it causes any problems over time. Participants are adults aged 18 to 80 with conditions like arthritis or hip fractures. The…

This study is tracking 100 people who received a total hip replacement with a specific implant called AMIStem C. The main goal is to see how much the implant moves inside the bone over time, using special X-ray analysis. Researchers will also check how well patients recover and h…

This study follows 300 adults aged 18-75 who received a specific type of hip implant (Quadra-P stem) during hip replacement surgery. The goal is to see how well the implant works over 10 years, including how long it lasts and how it improves pain and movement. Participants have c…

Researchers are comparing two common surgical approaches during total hip replacement: removing the acetabular labrum (a ring of cartilage around the hip socket) or leaving it in place. The trial enrolls 200 adults with hip osteoarthritis who are scheduled for a primary unilatera…

This study tests whether a supervised exercise program before hip or knee replacement surgery can improve recovery, function, and quality of life. 44 adults with advanced osteoarthritis will do 3 weekly physiotherapy sessions plus daily home exercises for several weeks before the…

This study tested whether a personalized exercise program done 2-4 weeks before knee or hip replacement surgery could improve thinking and reduce delirium in adults aged 55 and older. Participants wore activity trackers and used a smartphone app. The study was suspended, so resul…

This study looks at 600 hip or knee replacement patients to compare three different wound closure products: Sylke adhesive dressing, Exofin skin glue, and Suture Strip Plus. The goal is to see which method causes the fewest allergic skin reactions and gives the best scar appearan…

This study tests whether doing guided exercises at home via video calls can reduce pain and improve movement in people with hip or knee osteoarthritis. 110 participants will either receive remote exercise sessions or standard education about their condition. The goal is to see if…

This study tests whether a special traction pad placed between the patient and the surgery table can reduce numbness in the groin area after hip arthroscopy. About 120 patients having hip surgery at Northwestern Memorial Hospital will be asked about numbness and difficulty urinat…

This study tests whether adding ultrasound-guided nerve blocks before hip or knee replacement surgery can reduce pain and opioid use compared to standard pain management. 400 adults with osteoarthritis will be enrolled. The goal is to improve recovery and reduce side effects like…

This study looks at whether a 6-day course of oral steroids after orthopedic surgery can help reduce pain, nausea, and improve movement. About 500 adults having common surgeries like joint replacement or fracture repair will be randomly assigned to receive either standard care or…

This study tests if adding two extra nerve blocks to a standard one can improve pain control and recovery after hip replacement surgery. About 60 adults having hip surgery will be randomly assigned to receive either the standard block alone or the standard block plus the extra bl…

This study tests whether a special bioactive leg sleeve (Reparel) works better than standard TED compression stockings for reducing leg swelling, pain, and blood clot risk after hip replacement surgery. About 50 adults aged 18-89 having a first hip replacement will take part. The…

This early-stage trial tests whether injecting a person's own fat-derived stem cells into a painful arthritic hip is safe and might reduce pain. Researchers at Mayo Clinic are enrolling 24 adults aged 18-65 with hip osteoarthritis. The main goal is to check for side effects, whil…

This study tests whether an AI chatbot can help people with hip or knee osteoarthritis feel less conflicted and anxious about their treatment choices. About 100 adults with osteoarthritis will chat with the AI before seeing their surgeon. Researchers will measure changes in decis…

This study follows 60 adults getting hip or knee replacement to track their sleep before and up to 6 months after surgery. Participants use a special device and app to measure sleep quality, pain, and recovery. The goal is to learn when sleep returns to normal so doctors can give…

This study looks at over 110,000 people who had hip replacement surgery to see if a longer or shorter hip stem works better. It compares death rates, how often the hip implant needs to be replaced, and patient-reported pain and function. The goal is to find out which stem length …

This study is tracking 120 people who received a HYPE SCS hip stem during total hip replacement. Researchers will monitor how long the implant lasts, how satisfied patients are, and any complications over 5 years. The goal is to confirm the device is safe and works as intended in…

This study looks at whether using a patient decision aid during doctor visits helps people with severe hip or knee osteoarthritis make better choices about surgery. Researchers will track how informed patients feel, their involvement in decisions, and their pain, function, and qu…

This study follows 125 adults aged 18-75 who are getting a hip replacement with a new type of implant (the Trident II shell). The main goal is to see how long the implant lasts without needing another surgery. Researchers will also track patients' pain and function using a standa…

This study asks over 2,300 people with various joint conditions (like arthritis, fractures, and hip problems) to fill out surveys about their treatment preferences. Researchers want to learn how factors like pain, recovery time, cost, and surgery versus non-surgery affect patient…

This study follows 124 golfers who have hip, knee, or shoulder replacement surgery. Researchers track how many return to golf, how long it takes, and how their game and joint function change over a year. The goal is to give patients and doctors clear, realistic expectations about…

This study looks at how the Insignia hip stem moves inside the body after a hip replacement. About 25 people with hip arthritis will get special X-rays and CT scans over two years to check for any shifting. The goal is to see if the stem stays stable and to compare two different …

This study looks at why people with bone cancer (skeletal sarcoma) get more infections after joint replacement surgery than those with arthritis. Researchers will collect tissue and blood samples from 40 patients to compare immune and bacterial factors. The goal is to understand …

This study compares two treatments for a torn hip labrum in people aged 40 and older: arthroscopic surgery to repair the tear versus physical therapy alone. Researchers want to find out which approach leads to better hip function and less pain. The goal is to help doctors and pat…

This study tracks 26 adults under 70 getting a hip replacement to see how stable a new type of hip implant stays over 2 years. Using special X-rays, doctors measure tiny movements of the implant right after surgery and at 6 months, 1 year, and 2 years. The goal is to learn if the…