Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Vitamin e in hip implants: a Longer-Lasting fix?

NCT ID NCT01713062

Disease control Sponsor: Aesculap AG Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two types of hip implant liners—one with vitamin E and one without—to see which lasts longer and causes fewer problems like wear or bone damage. Researchers are following 400 adults aged 18 to 75 who need a hip replacement due to arthritis. The goal is to find out if the vitamin E liner reduces implant failure over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hip implant liner (highly cross-linked polyethylene with or without vitamin E)
What this could lead to
If successful, this could show that adding vitamin E to hip implant liners reduces wear and extends implant life, improving outcomes for hip replacement patients.
What could go wrong
This is a long-term study still in progress, so results are not yet final. The benefit of vitamin E may be small or not apply to all patients, and implant failure or complications remain possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

400 people

The number who actually took part.

Started

Jan 2012

Expected to finish

Jun 2030

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

adult patients

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion: * Minimum age: 18 years * Maximum age: 75 years * Indication of cementless THA * Approval of study participation and treatment according to study protocol * Physical and mental willingness of adhering to clinical and radiological follow up Exclusion: * Patient is not able to join follow up * Increased risk of anaesthesia according to the "American Society of Anesthesiology": ASA IV * Tumor disease * Alcohol and drug dependency * Permanent cortisone therapy * Clinical relevant infections * Pregnancy and planned pregnancy * Previous interventions like adjustment-osteotomy, treatment of fractures or THA on affected side * Acute fractures of the affected hip joint * Patients with bone quality, which doesn´t allow a cementless treatment * Requirements of clinical relevant deformities (condition after preoperation or bone fracture, leg length discrepancy \> 30 mm, Offset-reduction about \> 30 mm) * Small acetabular treatments with 28 mm heads * Treatments without using ceramic heads * Treatments which require neck prolonging components

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Arthritis are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

arthritic joint disease osteoarthritis, hip

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arthritis Osteoarthritis, hip

Contacts and locations

Locations

  • Elisabeth Klinikum Olsberg

    Olsberg, 59939, Germany

  • Fachklinik für Orthopädie, Unfallchirurgie, WirbelsäulenchirurgieMarienhaus Klinikum St. Josef

    Bendorf, 56170, Germany

  • Klinik für Orthopädie und Unfallchirurgie

    Bochum, 44791, Germany

  • Klinik und Poliklinik für Orthopädie

    Halle, 06097, Germany

  • Orthopädische Klinik der MHH im Annastift

    Hanover, 30625, Germany

  • St. Marien Hospital

    Mülheim, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.