Lumbar disk disease

This study looks at whether CT scans taken during lumbar spine surgery can detect spinal instability more reliably than standard X-rays taken before surgery. Researchers will review imaging and medical records from 100 adults undergoing surgery for degenerative spine conditions. …

Researchers compare three fluoroscopy-guided epidural steroid injection techniques for adults with leg pain from a herniated disc. Ninety-nine participants receive either a high-volume interlaminar injection, a low-volume interlaminar injection, or a transforaminal injection. The…

This study tests whether injecting platelet-rich plasma (PRP) into the epidural space during endoscopic disc herniation surgery can reduce nerve pain in the leg. PRP is made from the patient's own blood and may help healing and reduce inflammation. The trial will enroll 50 adults…

This study looks at two ultrasound-guided nerve blocks used to manage pain after lumbar spine surgery: the classic TLIP block and the QIP block. Adults aged 18-65 having elective lumbar discectomy will receive one of these blocks as part of their routine care. Researchers will tr…

This trial tests whether a hands-on spinal manipulation technique, called lever positioning manipulation, can ease the leg and back pain caused by a herniated disc. About 84 adults with a herniated disc will receive either the real manipulation or a sham version three times a wee…

This study tests whether giving magnesium during back surgery can reduce the confusion and agitation some patients feel when waking up. 70 adults having a single-level lumbar microdiscectomy will receive either magnesium or a placebo. Researchers will monitor agitation, pain, and…

This study looks at two ways to help people recover after surgery for a slipped disc in the lower back. One group will start moving early, and the other will do the same plus get mild electrical stimulation on their muscles. The goal is to see which approach reduces pain and impr…

This study will compare two types of nerve blocks—lumbar paravertebral block and lumbar erector spinae plane block—for pain control after lumbar spine surgery in people aged 65 and older. The goal is to see which block reduces the need for opioid painkillers in the first 48 hours…

This study compares two types of nerve blocks (thoracolumbar interfascial plane block and retrolaminar block) to see which one helps patients recover better after lumbar spine fusion surgery. 70 adults scheduled for surgery will receive one of the two blocks before the procedure.…

This study tests whether electroacupuncture can improve sleep in people with long-term sciatica caused by a slipped disc. About 114 adults with chronic insomnia and leg pain will receive either real electroacupuncture or a sham version three times a week for four weeks. Researche…

This study compares a specialized posture-correction exercise program (Mirror Image Spine Correction) with standard physiotherapy for adults with sciatica. Over 12 weeks, 64 participants will receive supervised sessions three times per week. The main goal is to see if the new exe…

This study looks at whether doing physical therapy in the daytime or evening helps people with a herniated disc in their lower back sleep better and feel less sleepy during the day. It includes 60 adults who also have a high risk for obstructive sleep apnea. Participants will be …

This study tests whether using virtual reality to educate patients before lumbar disc surgery reduces their anxiety more than standard education. About 56 adults scheduled for back surgery will be randomly assigned to either a VR education session or routine education. Researcher…

This study looks at people with a single herniated disc in the lower back who are getting laser disc surgery. Some will also receive a steroid injection during the same procedure. Researchers will track pain, daily function, and need for more treatments to see if the extra inject…

This study compares two surgical techniques for fusing bones in the lower back: using two straight cages or one curved (banana-shaped) cage. The goal is to see which method provides better pain relief, faster recovery, and fewer complications. About 30 adults with chronic back pa…

This study tests whether teaching patients how to move safely after lumbar stabilization surgery—using virtual reality videos and brochures before the operation—can reduce pain, anxiety, fear of movement, and fear of falling, and improve mobility. Sixty adults having their first …

This observational study looks at whether the size of two lower-back muscles, the psoas and multifidus, measured on MRI scans taken before surgery, is related to how well patients recover after surgery for a herniated disc. The study will include 100 adults aged 18 to 75 schedule…

This study will test two different levels of positive pressure (PEEP) on a breathing machine during lumbar spine surgery performed face-down. The goal is to see which setting helps patients breathe better and maintain good oxygen levels. Sixty adults aged 18-65 having elective ba…

This study reviews medical records of 120 adults with low back pain who completed 15 sessions of physical therapy. Researchers will group patients based on their MRI results (disc herniation, disc degeneration, or normal findings) to see if certain types of back pain respond bett…

This study looks at 96 adults with lower back pain to see if the damage shown on an MRI matches how much pain they actually feel. Participants will fill out pain and disability questionnaires and get a physical exam. The goal is to help doctors better understand and treat back pa…

This study will follow 120 adults with sciatica from a herniated disc who receive a standard steroid injection. Researchers want to see if the speed and pattern of pain relief in the first few days and weeks can predict whether the treatment is still working at 3 and 6 months. Pa…

This study will observe how different spinal problems—like scoliosis, stenosis, or herniated discs—change the way people walk and use their back muscles. Researchers will compare 120 older adults (age 60+) with these conditions to healthy volunteers using motion cameras and muscl…

This study compares two minimally invasive surgical techniques—uniportal and biportal endoscopy—for treating a single-level lumbar disc herniation. Sixty adults aged 18-70 with persistent symptoms will be randomly assigned to one of the two procedures. The main goal is to see whi…