Back surgery breathing study seeks safer anesthesia settings
NCT ID NCT07545733
First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times
Summary
This study will test two different levels of positive pressure (PEEP) on a breathing machine during lumbar spine surgery performed face-down. The goal is to see which setting helps patients breathe better and maintain good oxygen levels. Sixty adults aged 18-65 having elective back surgery under total intravenous anesthesia will take part.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged between 18 and 65 years * American Society of Anesthesiologists (ASA) physical status I-II * Scheduled for elective lumbar spine surgery in the prone position * Planned general anesthesia with total intravenous anesthesia (TIVA) * Ability to provide informed consent Exclusion Criteria: * Body mass index (BMI) ≥ 30 kg/m² * History of significant pulmonary disease (e.g., COPD, asthma) * Severe cardiovascular disease * Pregnancy * Known difficult airway * Requirement for intraoperative vasopressor infusion due to hemodynamic instability * Conversion to different surgical position or change in surgical plan * Incomplete data or protocol deviation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
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A doctor treating you
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Other studies related to the condition(s) this trial covers.
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