Which nerve block wins the battle against Post-Spine surgery pain?
NCT ID NCT07750418
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study looks at two ultrasound-guided nerve blocks used to manage pain after lumbar spine surgery: the classic TLIP block and the QIP block. Adults aged 18-65 having elective lumbar discectomy will receive one of these blocks as part of their routine care. Researchers will track how much opioid pain medication is needed in the first 24 hours, when pain medication is first requested, pain scores at several time points, and any side effects. The goal is to see which block provides better pain relief and reduces opioid use.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Two ultrasound-guided nerve blocks (TLIP and QIP) using bupivacaine, a local anesthetic
- What this could lead to
- If one block proves better, it could become the preferred method to reduce pain and opioid use after lumbar spine surgery.
- What could go wrong
- This is a small observational study, not randomized, so results may be influenced by patient differences. Blocks may not work equally for everyone and carry rare risks like infection or nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients aged 18-65 years, ASA physical status I-II, undergoing elective lumbar discectomy at up to two spinal levels under general anesthesia at Vezirköprü State Hospital, who receive either a classic TLIP block or a QIP block for postoperative analgesia as part of routine clinical practice.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18-65 years * ASA physical status I-II * Undergoing elective lumbar discectomy at up to two spinal levels under general anesthesia * Receiving classic TLIP block or QIP block for postoperative analgesia as part of routine clinical practice Exclusion Criteria: * Hypersensitivity or allergy to study medications * Coagulopathy * Infection at the injection site * Severe neurological deficit * Chronic opioid use * Advanced hepatic or renal failure * Obesity (BMI \>35 kg/m2) * Pregnancy * ASA physical status III-IV * Mental retardation * Inability to provide informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Vezirköprü State Hospital
Vezirköprü, Samsun, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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