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Keyhole surgery showdown: which technique works best for slipped discs?

NCT ID NCT07151651

Knowledge-focused Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study compares two minimally invasive surgical techniques—uniportal and biportal endoscopy—for treating a single-level lumbar disc herniation. Sixty adults aged 18-70 with persistent symptoms will be randomly assigned to one of the two procedures. The main goal is to see which technique provides better pain relief and surgical outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Endoscopic lumbar discectomy (surgical procedure)
What this could lead to
If successful, this could help surgeons choose the best endoscopic technique for treating herniated discs, potentially improving pain relief and recovery.
What could go wrong
This is a small, early-stage comparative study with only 60 participants, so results may not apply to all patients. Surgical risks like infection or nerve damage still apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2025

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All patients should fulfill the following criteria 1. Patients aged 18-70 years. 2. single-level lumbar disc herniation (L3-L4, L4-L5, or L5-S1) confirmed by MRI. 3. Persistent symptoms not responding to conservative management (≥6 weeks). Exclusion Criteria: * All patients should not have any of the following criteria 1. Multilevel disc herniation. 2. Previous lumbar spine surgery, trauma or injection. 3. Severe spinal stenosis. 4. Severe osteoporosis, infection, or malignancy or autoimmune disease affecting the spine. 5. Uncontrolled medical comorbidities contraindicating surgery. 6. Instability: spondylolisthesis\>grade 1 7. Marked obesity.(BMI \>35-40 kg/m2 )

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Conditions

The condition(s) this trial relates to.

Intervertebral Disc Displacement lumbar disk disease lumbar disk herniation, susceptibility to

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lumbar disc herniation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sohag University

    Sohag, Sohag Governorate, 002, Egypt

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