Chemotherapy-induced neuropathy

This study tests whether a special hand therapy program can prevent chemotherapy-induced nerve damage in the hands of people with pancreatic cancer. Participants are randomly assigned to either the hand therapy or traditional occupational therapy. The goal is to see if the hand t…

This study tested whether a diode laser can act as a biomarker to measure neuropathic pain in people with peripheral neuropathy. Researchers compared pain responses to a lidocaine patch versus a placebo patch in 75 participants. The goal was to see if the laser test could disting…

This study tested a new, non-invasive tool that measures skin conductance to detect small nerve fiber damage in children undergoing chemotherapy. Nerve damage is a common and serious side effect of cancer treatment, but current tests are often painful or not suitable for children…

This study tested whether tadalafil, a drug often used for erectile dysfunction, can prevent nerve damage caused by docetaxel chemotherapy in men with metastatic prostate cancer. 90 participants were randomly assigned to receive either tadalafil plus standard care or standard car…

This study tested whether omeprazole, a common heartburn medication, could prevent nerve damage caused by oxaliplatin chemotherapy in 46 adults with colorectal or pancreatic cancer. Participants took omeprazole before and during chemotherapy cycles. The goal was to see if it redu…

This study tested whether a web-based exercise program could reduce nerve pain and improve quality of life in breast cancer patients receiving chemotherapy. 90 patients with stage II-III breast cancer and neuropathy symptoms took part. The program was guided by a physiotherapist …

Researchers are testing three non-drug approaches for nerve pain caused by paclitaxel, a common chemotherapy for breast cancer. The trial enrolls 140 women receiving weekly paclitaxel who develop mild nerve symptoms. Participants are assigned to TENS, compression, cryotherapy, or…

This study tested whether electrostimulation and compression can reduce nerve pain and improve quality of life in people with gastrointestinal cancer who developed peripheral neuropathy from oxaliplatin chemotherapy. 140 patients were split into four groups: control, electrostimu…

This trial tests whether real acupuncture can reduce the numbness, tingling, and pain that chemotherapy often leaves behind. Cancer survivors with persistent nerve symptoms will receive either genuine acupuncture or a sham version with superficial needling at non-acupoints. The g…

This trial tests whether a sensory rehabilitation program, guided by physiotherapists, can reduce nerve pain and improve balance in people with chemotherapy-induced peripheral neuropathy (CIPN). Participants are adults who finished chemotherapy more than three months ago and repo…

This study investigates whether foot massage using a roller can reduce nerve pain caused by chemotherapy in cancer patients. About 80 adults receiving certain chemotherapy drugs will either receive foot massage twice daily for three weeks or continue with routine care. The goal i…

This trial tests whether mirogabalin, a newer pain medication, can reduce nerve pain caused by chemotherapy better than the standard drug duloxetine. Cancer survivors with peripheral neuropathy in their feet will take one of the two drugs daily for four weeks. The study measures …

This trial tests whether the Otago Exercise Program, a supervised routine of strengthening, balance, and walking exercises, can reduce muscle weakness in people with chemotherapy-induced peripheral neuropathy (CIPN). About 48 adults aged 35-55 who have received taxane chemotherap…

This study tests whether a mobile app can teach family caregivers safe massage techniques to help cancer survivors with long-term nerve pain and numbness caused by chemotherapy. About 300 participants (survivors and their caregivers) will use the app at home. The goal is to reduc…

This study tests whether pressing specific points on the ear (auricular point acupressure) can reduce pain, numbness, and tingling caused by chemotherapy. About 225 cancer patients will try this non-needle technique. Researchers will also measure changes in nerve function and bod…

This study tests whether a wearable device that vibrates the legs can help relieve persistent nerve pain and numbness caused by chemotherapy. The device, called Myovolt, is worn on the legs for about 30 minutes twice a day. Researchers are looking at how practical and acceptable …

This study tests whether graded motor imagery—a brain-based therapy involving left/right judgment, imagined movements, and mirror exercises—can relieve nerve pain and improve leg function in cancer patients with chemotherapy-induced peripheral neuropathy. Half the participants wi…

This study tests whether acupuncture can reduce the nerve pain, numbness, and tingling that often lingers after chemotherapy. Cancer survivors who completed chemo at least three months ago will receive either real acupuncture, a sham (fake) version, or no extra treatment. The goa…

This completed pilot study tested a behavioral program called PIVOT in 33 adults with chemotherapy-induced peripheral neuropathy. Participants worked with coaches to set personal health goals using a structured goal-setting method. The study aimed to see if this approach is safe …

This study tests a device that cools and compresses the arms and legs to see if it can prevent nerve damage caused by chemotherapy. The device is first tested in healthy volunteers to find the best temperature and pressure, then in cancer patients receiving weekly paclitaxel. The…

This study looked at how common nerve pain is in cancer patients getting chemotherapy and tested if a simple exercise program could help. 282 patients took part, and those who did supervised exercises for 21 days reported less nerve pain than those who got usual care. The results…

This study tested whether roasted nux vomica capsules can help with nerve pain caused by the chemotherapy drug bortezomib in multiple myeloma patients. Twenty-two participants took the capsules for six weeks while continuing their regular chemo. Researchers measured changes in ne…

This pilot study tested whether electro-acupuncture—a treatment that combines traditional acupuncture with mild electrical current—is practical and helpful for people with nerve pain and numbness from chemotherapy. Twenty cancer survivors who had completed chemotherapy at least t…

This study tested whether injecting platelet-rich plasma (PRP) near nerves can reduce pain and nerve damage caused by chemotherapy. 62 cancer patients with persistent nerve pain received PRP injections guided by ultrasound. Researchers measured pain levels and nerve function to s…

This pilot study tested whether acupuncture could reduce tingling, numbness, and pain in the hands and feet caused by chemotherapy in breast cancer survivors. Fifty-seven women who had completed taxane-based chemotherapy were randomly assigned to receive acupuncture immediately o…

This study tested whether Pilates or Gyrotonic exercises can ease nerve pain and reduce fall risk in 100 cancer survivors who have nerve damage from chemotherapy. Participants did one of the two exercise programs. The goal was to see if these exercises improve symptoms like numbn…

This study tested whether acupuncture can help prevent or reduce nerve pain, numbness, and tingling caused by chemotherapy in people with early-stage breast cancer. 89 participants were split into two groups: one received acupuncture, the other watched nature videos and did relax…

This study tested a topical cannabidiol (CBD) cream against a placebo cream to see if it could reduce nerve pain, numbness, and tingling in the hands and feet caused by chemotherapy. Forty adults with moderate to severe chemotherapy-induced peripheral neuropathy (CIPN) applied th…

This study tested a dietary supplement containing ingredients like palmitoylethanolamide, alpha lipoic acid, and several B vitamins to see if it could reduce nerve pain in cancer patients receiving chemotherapy. 71 newly diagnosed patients who had not yet started treatment took e…

This study looked at whether adding extra sensory feedback to physical therapy could improve balance and reduce fall risk in women with nerve damage from cancer treatment. Forty women who had recovered from breast cancer took part. The group that received the extra sensory feedba…

This study looked at whether taking daily vitamin B complex can help prevent or reduce nerve pain (peripheral neuropathy) caused by the chemotherapy drug paclitaxel in women with ovarian cancer. 146 adult women took part. Half took vitamin B pills every day for 6 months while get…

This pilot study tested whether sound acupuncture — using tuning forks on energy points instead of needles — can reduce nerve pain caused by chemotherapy. Forty adults with chemotherapy-induced neuropathy took part. Half received standard medical therapy alone, and half received …

This study tested whether group dance classes can improve balance and motivation in breast cancer survivors who have nerve damage from chemotherapy. Fifty-two survivors participated in either dance-based exercise or standard exercise for several weeks. The goal was to see if danc…

This completed study looked at how nerve damage from the chemotherapy drug oxaliplatin affects hand function, grip strength, and quality of life in 103 colorectal cancer patients. Researchers measured hand and finger strength, dexterity, and daily living abilities using standard …

This study involved 50 people with gastrointestinal cancer who had nerve pain from the chemotherapy drug oxaliplatin. Researchers interviewed patients to understand their symptoms and how the pain affected their daily life. The goal was to use this information to design a medical…

This study tested whether brief smartphone surveys can help detect early signs of fall risk in people receiving chemotherapy that can cause nerve damage. Twelve cancer patients used a mobile app to report symptoms like numbness or tingling in their legs. The goal was to see if pa…

This study looked at 120 women with early-stage breast cancer to see if having low muscle mass (sarcopenia) before treatment raises the risk of nerve damage from the chemotherapy drug paclitaxel. Researchers measured muscle mass on CT scans and checked for nerve symptoms using qu…

This study looked at how common nerve damage is in adults who had vincristine chemotherapy for childhood leukemia. 467 survivors were assessed using a questionnaire about nerve symptoms. The goal was to understand how often and how severe this side effect is long after treatment …