Vitamin b may shield ovarian cancer patients from chemo nerve damage
NCT ID NCT07191587
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether taking daily vitamin B complex can help prevent or reduce nerve pain (peripheral neuropathy) caused by the chemotherapy drug paclitaxel in women with ovarian cancer. 146 adult women took part. Half took vitamin B pills every day for 6 months while getting weekly chemo, and the other half did not. Researchers tracked their nerve pain symptoms to compare the two groups.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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146 people
The number who actually took part.
- Started
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Dec 2024
- Finished
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May 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female patients with confirmed pathology of ovarian adenocarcinoma. * Aged 18 years or older. * Scheduled to receive a weekly paclitaxel-based chemotherapy regimen (80 mg/m²). Exclusion Criteria: * Individuals under 18 years of age. * Any patients with pre-existing peripheral neuropathy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Cancer Institute
Cairo, 11796, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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