PRP shots may ease nerve pain from chemo
NCT ID NCT05348408
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether injecting platelet-rich plasma (PRP) near nerves can reduce pain and nerve damage caused by chemotherapy. 62 cancer patients with persistent nerve pain received PRP injections guided by ultrasound. Researchers measured pain levels and nerve function to see if the treatment helped.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- platelet-rich plasma (PRP)
- What this could lead to
- If it works, this could provide a new way to reduce nerve pain and improve quality of life for cancer patients suffering from chemotherapy side effects.
- What could go wrong
- This is a small, early-phase trial with only 62 participants, so results may not apply to everyone. The treatment involves injections, which carry risks like infection or discomfort.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
62 people
The number who actually took part.
- Started
-
Apr 2022
- Finished
-
Dec 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * cancer patients with peripheral neuropathy confirmed by clinical evaluation and nerve conduction study despite of medical treatment Exclusion Criteria: patients with: * Foot ulcers and / or amputation. * Peripheral vascular disease. * Uncontrolled diabetes * Vertebral pathologies. * Connective tissue diseases. * Thyriod disorders, significant renal or hepatic dysfunction. * Platelet dysfunction syndrome, critical thrombocytopenia. * Septicemia and local infection at the site of the procedure. * Systemic corticosteriod adminstiration or local injection at the suspected treatment site within the last month. * Recent fever or illness. * Hemoglobin level less than 10 g/dl, platelet count less than 105-109/L.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Pain clinic and intervention unit at South Egypt Cancer Institute, Assuit University
Asyut, Egypt, 71514, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Retraining the senses to fight chemotherapy nerve damage
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- Chilling out Chemo's side effects: could cold therapy shield nerves?
- Essential oils vs. chemo nerve pain: a natural remedy put to the test