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Painless skin test spots nerve damage in kids after chemo

NCT ID NCT04262778

Diagnosis Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new, non-invasive tool that measures skin conductance to detect small nerve fiber damage in children undergoing chemotherapy. Nerve damage is a common and serious side effect of cancer treatment, but current tests are often painful or not suitable for children. The goal was to see if this simple device could accurately identify nerve problems early, which could help doctors manage symptoms and improve quality of life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

55 people

The number who actually took part.

Started

Oct 2020

Finished

Sep 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Child receiving a Potentially Neurotoxic Chemotherapy

Ages

5 to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * aged 5-17 years * initiating a potentially neurotoxic chemotherapy alkaloids (vincristine vinblastine, vinorelbine), Platinum compounds (oxaliplatine, cisplatine, carboplatine), proteasome inhibitors (bortezomib), Thalidomide derivatives, taxanes (such as taxol or taxotere), antiCD30 (brentuximab) * Information of the legal representative of the patient Affiliated to social security regime or an equivalent system Exclusion Criteria: * history of peripheric neuropathy * current antiepileptic medications or other treatment for neurogenic pain (tegretol, neurontin, lyrica, laroxyl, rivotril,… etc) * distal skin lesions that do not allow electrochemical skin conductance measurement * child not able to stand during the time of examination

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chemotherapy-induced peripheral neuropathy

Contacts and locations

Locations

  • Necker- enfants maladies hospital

    Paris, 75015, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.