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Exercise from home may ease chemotherapy nerve damage in breast cancer patients

NCT ID NCT06879678

Symptom relief Sponsor: Bilecik Seyh Edebali Universitesi Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Sep 15, 2026 · Updated 3 times

Summary

This study tested whether a web-based exercise program could reduce nerve pain and improve quality of life in breast cancer patients receiving chemotherapy. 90 patients with stage II-III breast cancer and neuropathy symptoms took part. The program was guided by a physiotherapist and lasted 8 weeks. Researchers measured symptoms and quality of life before and after the program.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Web-based exercise program
What this could lead to
If it works, this could offer a simple, drug-free way to reduce nerve pain and improve daily life for breast cancer patients on chemotherapy.
What could go wrong
This is a small, completed trial with 90 participants. The exercise program is behavioral, so results may vary, and it may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

95 people

The number who actually took part.

Started

May 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Able to understand and speak Turkish, * Over 18 years of age, * Receiving taxane-based chemotherapy in daytime chemotherapy units, * Reporting at least one neuropathy symptom according to CIPNAT, * Diagnosed with stage II-III breast cancer, * Receiving a planned weekly taxane-based chemotherapy infusion dose (70-99 mg/m², 100-129 mg/m², 130-159 mg/m², 160 mg/m² and above) and completing 8 treatment cycles, * Having internet access, * No history of deep vein thrombosis, * Not using anticoagulant medication, * Willing to participate in the study. Exclusion Criteria: * Younger than 18 years or older than 75 years, * Having central nervous system disorders affecting movement, balance, sensation, or coordination, * Presence of any skin infection, scar tissue, inflammation, or incision on the hands or ankles, * Diagnosed with a proven cardiac condition or using medication for cardiac issues, * Pregnant women or those in the postpartum period, * History of polyneuropathy before chemotherapy, * Cognitive impairment, * Presence of metal implants in the exposure area, * History of any other malignancy, * Undergoing mastectomy. Withdrawal Criteria * Patients meeting the following conditions will be withdrawn from the study: * Patients whose taxane treatment protocol is changed, * Patients who wish to withdraw from the study, * Patients with a pulse rate above 100 bpm, * Patients receiving fewer than four weekly chemotherapy applications, * Women without internet access or those who do not visit the website at least five times for four hours throughout the follow-up period.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm chemotherapy-induced neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Chemotherapy induced peripheral neuropathy (CIPN)

Contacts and locations

Locations

  • Gulhane Education and Research Hospital, Ankara, 06010

    Ankara, 06010, Turkey (Türkiye)

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