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Vitamin cocktail may soothe chemo nerve damage

NCT ID NCT07022938

Symptom relief Sponsor: Aristotle University Of Thessaloniki Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a dietary supplement containing ingredients like palmitoylethanolamide, alpha lipoic acid, and several B vitamins to see if it could reduce nerve pain in cancer patients receiving chemotherapy. 71 newly diagnosed patients who had not yet started treatment took either the supplement or a placebo. The goal was to measure changes in neuropathic pain symptoms and nerve function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dietary supplement (palmitoylethanolamide, alpha lipoic acid, vitamins B1, B6, B12, E, nicotinamide, magnesium, zinc, superoxide dismutase)
What this could lead to
If it works, this supplement could offer a simple way to reduce nerve pain caused by chemotherapy, improving quality of life for cancer patients.
What could go wrong
This is a small, completed phase 4 trial with only 71 participants. The supplement may not work for everyone, and results may not apply to all chemotherapy types. Dietary supplements can also interact with other medications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

71 people

The number who actually took part.

Started

Nov 2021

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Newly diagnosed patients with cancer that have not received yet their treatment * Patients that will be treated with platinum agents or taxanes Exclusion Criteria: * Not receiving dietary supplement * Have already neuropathy * Have already started chemotherapy * Patients with uncontrolled diabetes \-- Patients with chronic kidney disease * Patiens with recent cardiovascular incident

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Conditions

The condition(s) this trial relates to.

cancer neoplasm peripheral neuropathy chemotherapy-induced neuropathy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer Chemotherapy induced pain neuropathy Chemotherapy-induced peripheral neuropathy Neuropathy

Contacts and locations

Locations

  • University General Hospital of Thessaloniki AHEPA

    Thessaloniki, Greece

More trials for these conditions

Other studies related to the condition(s) this trial covers.