Vitamin cocktail may soothe chemo nerve damage
NCT ID NCT07022938
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a dietary supplement containing ingredients like palmitoylethanolamide, alpha lipoic acid, and several B vitamins to see if it could reduce nerve pain in cancer patients receiving chemotherapy. 71 newly diagnosed patients who had not yet started treatment took either the supplement or a placebo. The goal was to measure changes in neuropathic pain symptoms and nerve function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dietary supplement (palmitoylethanolamide, alpha lipoic acid, vitamins B1, B6, B12, E, nicotinamide, magnesium, zinc, superoxide dismutase)
- What this could lead to
- If it works, this supplement could offer a simple way to reduce nerve pain caused by chemotherapy, improving quality of life for cancer patients.
- What could go wrong
- This is a small, completed phase 4 trial with only 71 participants. The supplement may not work for everyone, and results may not apply to all chemotherapy types. Dietary supplements can also interact with other medications.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University General Hospital of Thessaloniki AHEPA
Thessaloniki, Greece
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