Vitamin cocktail may soothe chemo nerve damage

NCT ID NCT07022938

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a dietary supplement containing ingredients like palmitoylethanolamide, alpha lipoic acid, and several B vitamins to see if it could reduce nerve pain in cancer patients receiving chemotherapy. 71 newly diagnosed patients who had not yet started treatment took either the supplement or a placebo. The goal was to measure changes in neuropathic pain symptoms and nerve function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dietary supplement (palmitoylethanolamide, alpha lipoic acid, vitamins B1, B6, B12, E, nicotinamide, magnesium, zinc, superoxide dismutase)

What this could lead to

If it works, this supplement could offer a simple way to reduce nerve pain caused by chemotherapy, improving quality of life for cancer patients.

What could go wrong

This is a small, completed phase 4 trial with only 71 participants. The supplement may not work for everyone, and results may not apply to all chemotherapy types. Dietary supplements can also interact with other medications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer neoplasm peripheral neuropathy chemotherapy-induced neuropathy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University General Hospital of Thessaloniki AHEPA

    Thessaloniki, Greece