Ankle injury
MONDO:0043895Harm or hurt to the ankle or ankle joint usually inflicted by an external source.
Also known as: ankle injury, injury of ankle, injury of tarsal region, tarsal region injury, Injuries, ankle, Injuries, syndesmotic, Sprains, ankle, ankle Sprains
173 clinical trials for this condition and its sub-types, 81 tagged with Ankle injury itself.
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New ankle rehab aims to cut repeat sprains
Disease control CompletedThis study compares a new sensorimotor ankle rehabilitation training (SMART) program to standard care for people with a first-time ankle sprain. The goal is to see if SMART reduces re-injury rates and improves quality of life over one year. Researchers will enroll 150 participant…
Sponsor: Phillip Gribble • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Keyhole surgery for ankle instability: a less invasive fix?
Disease control CompletedThis trial compares two surgical techniques for repairing a torn ligament in the ankle that causes chronic instability after repeated sprains. One approach uses a minimally invasive arthroscope, while the other is the standard open Broström procedure. The study will measure outco…
Sponsor: Peking University People's Hospital • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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Dissolvable screws could spare ankle fracture patients a second surgery
Disease control CompletedThis study looked at using bioabsorbable (dissolvable) screws instead of metal screws to fix a specific type of ankle injury called syndesmosis disruption. The goal was to see if these screws could hold the bones in place while they heal, then naturally dissolve, avoiding the nee…
Sponsor: NHS Grampian • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New skin patch could replace flap surgery for leg injuries
Disease control CompletedThis study compared two ways to cover deep wounds on the lower leg, ankle, or foot: a synthetic skin patch called Integra versus traditional flap surgery (moving skin from another body part). 72 patients with traumatic skin loss were enrolled. The goal was to see which method lea…
Phase 3 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Can stronger ankles change how you walk?
Prevention CompletedResearchers at the University of Ljubljana studied whether a 12-week ankle strength training program changes muscle strength and walking mechanics in healthy, active men aged 18 to 50. Participants trained on a device that isolates the muscles that turn the foot outward and inwar…
Sponsor: University of Ljubljana • Aim: Prevention
Last updated Sep 17, 2026 00:00 UTC
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Army tests strength and balance drills to stop ankle sprains in recruits
Prevention CompletedThis study tested whether a program of strength and balance exercises could help prevent ankle sprains in new army recruits. 786 soldiers aged 18-22 took part. They were assessed before and after the exercise program to see if their ankle stability, balance, and muscle strength i…
Sponsor: University of Haifa • Aim: Prevention
Last updated Jun 27, 2026 08:14 UTC
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Laser light could take the ouch out of ankle sprains
Symptom relief CompletedThis study tests whether a device called LightForce® Therapy Laser can reduce pain from mild to moderate ankle sprains. About 108 adults with acute ankle sprain pain will receive either real laser therapy or a sham (fake) laser, plus standard care like rest and ice. The main goal…
Sponsor: DJO UK Ltd • Aim: Symptom relief
Last updated Aug 29, 2026 00:00 UTC
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Biofeedback may sharpen knee awareness after old injuries
Symptom relief CompletedThis pilot study tests whether a 3-week knee exercise program with visual and audio feedback can improve joint awareness (proprioception) and movement quality in adults aged 18–64 who had a knee injury at least a year ago. Participants complete both a supervised lab-based biofeed…
Sponsor: Marshall University • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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New rehab method may speed ankle sprain recovery
Symptom relief CompletedThis study tested whether adding perturbation-based training (unexpected movements) to standard foot-intensive rehabilitation helps people recover from ankle sprains. 36 adults aged 18-35 with recent ankle sprains were split into two groups and treated for 6 weeks. Researchers me…
Sponsor: University of Lahore • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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Can Non-Opioid painkillers replace opioids after ankle surgery?
Symptom relief CompletedThis study tested whether a non-opioid pain regimen (celecoxib plus acetaminophen) works as well as an opioid regimen (oxycodone plus acetaminophen) for pain after ankle arthroscopy. 112 adults were randomly assigned to one of the two groups. The goal is to find a safer way to ma…
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New long-lasting painkiller may cut opioid use after foot surgery
Symptom relief CompletedThis study tested whether a long-acting painkiller called Exparel (liposomal bupivacaine) works better than the standard version for numbing the foot and ankle during and after surgery. About 248 adults having elective foot or ankle surgery received either Exparel or standard bup…
Phase 4 • Sponsor: St. Luke's Hospital, Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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New device may speed up ankle sprain recovery
Symptom relief CompletedThis study tested whether adding TECAR therapy (a device that uses electrical currents) to standard exercises improves balance, pain, and daily function after an acute ankle sprain. 42 adults with grade I or II sprains were split into two groups: one did exercises alone, the othe…
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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New gel combo for aching muscles: does it beat standard pain relievers?
Symptom relief CompletedThis study tested whether a gel containing piroxicam plus warming and cooling ingredients (methyl salicylate, menthol, eugenol) works as well as standard piroxicam-only or diclofenac gels for muscle and joint pain. 180 adults with conditions like ankle sprain, back pain, or knee …
Phase 3 • Sponsor: Taisho Pharmaceutical Indonesia • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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New foot training shows promise for ankle sprain relief in athletes
Symptom relief CompletedThis study looked at whether a program called Hyperarch Fascia Training (HFT) can reduce ankle pain and improve jumping ability in active adults aged 20-45 who have had ankle sprains. 62 participants were split into two groups: one did HFT exercises remotely for 12 weeks, while t…
Sponsor: Applied Science & Performance Institute • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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ER osteopathy eases ankle sprains: study tests One-Time fix
Symptom relief CompletedThis study tested whether a single osteopathic session in the emergency department can improve recovery from a mild to moderate ankle sprain. Fifty adults with recent sprains were split into two groups: one got standard medical care, the other got osteopathic treatment. Researche…
Sponsor: CHU de Reims • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Nerve stretching may ease Long-Term ankle pain
Symptom relief CompletedThis study looked at whether adding nerve mobilization exercises to standard balance training can improve pain, movement, and function in people with chronic ankle instability. Thirty-six adults with a history of ankle sprains and ongoing instability participated. The results cou…
Sponsor: National Yang Ming Chiao Tung University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Teen ankle sprain study: which rehab approach works best?
Symptom relief CompletedThis study looked at two ways to help teenagers recover from a first-time ankle sprain. One group used the traditional PRICE method (rest, ice, compression, elevation) plus ibuprofen. The other group used a newer approach called PEACE and LOVE, which avoids anti-inflammatory drug…
Sponsor: Lithuanian University of Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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New patch could ease ankle sprain pain without pills
Symptom relief CompletedThis study tested a medicated patch containing esflurbiprofen, a pain-relieving drug, against a placebo patch in 69 adults with mild ankle sprains. Participants wore the patch for 7 days. The goal was to see if the patch reduces pain during movement better than a placebo. The tri…
Phase 3 • Sponsor: Teikoku Seiyaku Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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New Mind-Body approach for wobbly ankles shows promise
Symptom relief CompletedThis study tested a new type of physical therapy that also addresses fear of movement in 36 people with chronic ankle instability. Participants attended sessions over 3 weeks, and researchers measured how many completed the program, changes in balance, and quality of life. The go…
Sponsor: Creighton University • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Laser and tape ease ankle sprain pain in new study
Symptom relief CompletedThis study looked at whether low-level laser therapy combined with kinesio taping helps people with mild to moderate ankle sprains. 62 adults aged 20-40 with recent sprains took part. Researchers measured pain, range of motion, and ankle function to see if the treatments worked.
Sponsor: University of Lahore • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Scientists track hidden muscle delays after ACL repair
Knowledge-focused CompletedThis study looks at how the thigh muscles (quadriceps and hamstrings) turn on during movement in people who have had ACL knee surgery. Researchers want to understand if muscle timing problems remain even after standard rehab. The study involves 25 men aged 18-45 who are 6 months …
Sponsor: KTO Karatay University • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Wearable tech could predict soldier injuries before they happen
Knowledge-focused CompletedThis study tested whether small body-worn sensors can predict if a soldier might get a leg injury during military training. Over 1,800 active-duty soldiers took part. The sensors measured balance and agility to see if they could spot who is at higher risk.
Sponsor: University of Miami • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Ultrasound for ankle sprains: game changer or just a picture?
Knowledge-focused CompletedThis study explored whether getting an ultrasound a few days after an ankle sprain leads to better recovery after 3 months. Researchers observed 13 patients who had a follow-up visit between day 3 and day 6 after injury. The goal was to see if the ultrasound helped doctors better…
Sponsor: Hopital Nord Franche-Comte • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Ankle surgery outcomes under the microscope
Knowledge-focused CompletedThis study reviewed medical records of 107 patients who had surgery for a broken ankle (distal fibula fracture) using metal plates. Researchers looked at X-rays to see when the bone healed and asked patients about their function and pain one year after surgery. The goal was to be…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Healthy ankle norms for soldiers could speed injury recovery
Knowledge-focused CompletedThis study measures normal ankle function in 96 healthy military personnel using the Ankle-Go test, which combines physical exercises and questionnaires. The goal is to establish reference values for soldiers, who have different physical demands than civilians. Results will help …
Sponsor: Direction Centrale du Service de Santé des Armées • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Wearable sensors and AI could predict leg injuries before they happen
Knowledge-focused CompletedThis study looked at 108 healthy sports science students to see if past leg injuries leave lasting changes in walking and running patterns. Participants wore small sensors on their legs while walking and running, and filled out questionnaires about their injury history. The goal …
Sponsor: Technical University of Munich • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Ankle instability holds athletes back: study shows clear performance gaps
Knowledge-focused CompletedThis study compared 16 athletes with chronic ankle instability (CAI) to 16 healthy athletes. They performed tests like jumps, hops, and agility runs. Results showed that those with CAI jumped lower, hopped shorter distances, and were slower in agility tests. The study suggests th…
Sponsor: Ankara Yildirim Beyazıt University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:37 UTC
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Taping fails to boost performance in teens with ankle instability
Knowledge-focused CompletedThis study tested whether kinesiotape or dynamic tape improves jumping and hopping performance in 29 adolescent volleyball players with mild ankle instability. Players performed functional tests with and without tape. The results showed no significant difference between taped and…
Sponsor: Yeditepe University • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:59 UTC
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Scientists uncover hidden foot muscle changes after ankle sprains
Knowledge-focused CompletedThis study looked at how foot and ankle joints move and bear weight during running in people with chronic ankle instability, those who recovered from a sprain, and healthy individuals. Researchers used cameras and pressure plates to measure joint angles and forces, and ultrasound…
Sponsor: Université Catholique de Louvain • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:02 UTC