New foot training shows promise for ankle sprain relief in athletes

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Gender: Male or females * Age: 20-45 years old * History of Chronic Ankle Sprains has led to present symptoms such as current pain and/or instability during weight-bearing activities, but no reported chronic knee, hip, or groin issues (within the past 3-months). * Cumberland Ankle Instability Tool (CAIT) score ≤ 25, indicating significant instability in at least one ankle (Wright et al. 2014). * Participants will be either recreationally trained, or considered trained/developmental as defined by McKay et al. (2021). Specifically, recreationally trained will be defined as meeting the World Health Organization (WHO) minimum activity guidelines of: minimal activity of at least 150-300 minutes of moderate-intensity activity, or 75-150min of vigorous-intensity activity a week; plus, muscle-strengthening activities 2 or more days a week. Recreationally trained participants may also participate in multiple sports/forms of activity. Trained/developmental will be defined as regularly training \~3 times per week, identifying with a specific sport, training with a purpose to compete. There is no performance standard required for these tiers. * Health Status: Free from chronic diseases, cardiovascular conditions, and musculoskeletal injuries unrelated to ankle sprains. * Be willing to attend a weekly one hour virtual training session on HFT plus a written program to be performed individually in two sessions for an additional 2 hours per week performed on their own. In total, be willing to train for up to 3-5 hours weekly on ankle rehabilitation. * Agree to maintain their usual activity levels and avoid additional treatment modalities for the duration of the study. * Have a iPhone smart phone XR (2018), or later model * Have a desktop computer or laptop, with a camera for video conference calls and online training. * Have a location with a minimum of 10ft \* 10ft space for exercise movement, and appropriate ceiling height for vertical jump testing. Exclusion Criteria: * History of Achilles tendon rupture or surgery within the last 12 months. Use of prescribed corticosteroids or other tendon-specific treatments within four weeks prior to the study. * Current enrollment in any structured fascial or tendon rehabilitation programs. * Pregnancy, breastfeeding, or plans to become pregnant during the study period. * Any medical conditions that may interfere with running or exercise performance or study participation. * Not willing to sign an NDA regarding the fascia training techniques used in this study * Use of medical interventions, such as growth hormone or peptides, that may influence tissue adaptation to exercise. * Current supplementation with common soft-tissue ingredients, such as glucosamine, chondroitin, methylsufonylmethane (MSM), or collagen protein. * Presents with Ehlers-Danlos syndrome (EDS) or hypermobility History or current drug abuse * History or current cigarette smoke (including vaping) within the past 14 days from the screening visit * Insulin-dependent diabetes and/or metformin use * Chronic kidney or liver disease * Has significant concurrent illnesses (controlled or uncontrolled), such as diabetes, lupus, epilepsy, or cardiac disorders, hepatitis B/C, HIV, serious mental health illness such as dementia or schizophrenia; psychiatric hospitalization in the past two years, or other, which in the opinion of the investigator, such conditions might be aggravated as a result of treatment * Clinically diagnosed as depressed or taking depression or anti anxiety medication * The investigator feels that for any reason the subject is not eligible to participate in the study * History of uncontrolled cardiovascular disease (i.e., myocardial infarction, hypertension, hypercholesterolemia, peripheral vascular disease, other) * Developmental disability or cognitive impairment that would preclude adequate comprehension of the informed consent form and/or ability to follow study subject requirement and/or record the necessary study measurements * Currently has been diagnosed with cancer or has been in remission for less than 1 year * Participation in any other investigational study within 30 days prior to consent.