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Safer pain relief after ankle surgery? Non-Opioid approach tested

NCT ID NCT07154433

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 28 times

Summary

This study tests whether a non-opioid pain medicine combination (celecoxib plus acetaminophen) works as well as an opioid-based combination (oxycodone plus acetaminophen) for pain after minimally invasive ankle surgery. 110 adults aged 18-65 will be randomly assigned to one of the two groups. The goal is to find a safer way to manage pain that avoids opioid risks like addiction and breathing problems.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 2nd Affiliated Hospital, School of Medicine, Zhejiang University, China

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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