New pacing technique could improve heart function in AF and heart failure patients

NCT ID NCT07560891

Not yet recruiting Disease control Sponsor: Yonsei University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a newer pacing method called Left Bundle Branch Area Pacing (LBBAP) with the standard coronary sinus pacing for cardiac resynchronization therapy in 44 adults who have both permanent atrial fibrillation and heart failure. The goal is to see if LBBAP better improves the heart's pumping ability over 12 months. Participants are randomly assigned to receive one of the two pacing approaches.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Left Bundle Branch Area Pacing (LBBAP) device
What this could lead to: If successful, this could offer a more effective pacing option for heart failure patients with atrial fibrillation, potentially improving heart function better than current standard therapy.
What could go wrong: This is a small early-stage trial with only 44 participants, so results may not apply to everyone. The new pacing method also carries risks like any heart device procedure, including infection or lead displacement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation cardiomyopathy heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (AF) CARDIOMYOPATHIES HEART FAILURE

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