Soy showdown: processed vs. natural – which lowers blood pressure best?

NCT ID NCT06907862

First seen May 14, 2026

Summary

This 12-week study tests whether replacing highly processed soy foods (like soy burgers) with less processed options (like tofu or edamame) can lower blood pressure and improve heart health in 300 adults with obesity, hypertension, and often type 2 diabetes. Participants use a digital app and get extra vegetables and fruit. The goal is to see if simple food swaps, combined with a guided diet program, work better than usual care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • C. David Naylor Building

    RECRUITING

    Toronto, Ontario, L6A 1N9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

soy protein foods (both highly processed and minimally processed) plus a vegetable and fruit blend

What this could lead to

If it works, this could show that simple food swaps—like choosing tofu over soy burgers—help manage blood pressure and heart health without extra medication.

What could go wrong

This is a 12-week diet study, not a drug trial, so results may be modest. Participants must follow strict daily food rules, which can be hard to stick with in real life.

Conditions

The condition(s) this trial relates to.

Dyslipidemias hypertensive disorder inherited lipid metabolism disorder obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.