Soy showdown: processed vs. natural – which lowers blood pressure best?
NCT ID NCT06907862
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This 12-week study tests whether replacing highly processed soy foods (like soy burgers) with less processed options (like tofu or edamame) can lower blood pressure and improve heart health in 300 adults with obesity, hypertension, and often type 2 diabetes. Participants use a digital app and get extra vegetables and fruit. The goal is to see if simple food swaps, combined with a guided diet program, work better than usual care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- soy protein foods (both highly processed and minimally processed) plus a vegetable and fruit blend
- What this could lead to
- If it works, this could show that simple food swaps—like choosing tofu over soy burgers—help manage blood pressure and heart health without extra medication.
- What could go wrong
- This is a 12-week diet study, not a drug trial, so results may be modest. Participants must follow strict daily food rules, which can be hard to stick with in real life.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
C. David Naylor Building
RECRUITINGToronto, Ontario, L6A 1N9, Canada
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