University Of Toronto

This study is testing if the timing of daily eating affects blood sugar control. Researchers are comparing three different 9-hour eating windows in 120 adults with obesity who have type 2 diabetes or are at risk for it. The goal is to see if starting meals earlier or later in the…

This study is testing if adding an old HIV drug, efavirenz, to a person's current treatment can kill cells that are still producing small amounts of HIV. It focuses on people whose virus levels are very low but still detectable despite excellent treatment adherence. The goal is t…

This study is testing whether adding a digital heart health program—including an app and online coaching sessions—to a person's usual medical care is better at controlling cholesterol and preventing heart attacks and strokes than usual care alone. It will involve about 1,100 adul…

This study is testing whether short, frequent bursts of physical activity (like walking breaks after meals) are as good as a standard 30-minute workout for controlling blood sugar in breast cancer survivors taking hormone therapy. It will involve 24 sedentary, postmenopausal wome…

This study is testing how well exercise and diet advice work to improve heart and metabolic health in women before and after menopause. Researchers will compare three groups: one doing exercise, one doing exercise plus getting diet advice, and one doing light stretching. The goal…

This study is testing whether exercise, or exercise combined with diet counseling, can improve heart health and body composition in breast cancer survivors. It will involve 45 women who have completed treatment and are now at risk for metabolic problems. Participants will be rand…

This study is testing if a 16-week supervised exercise and lifestyle program can improve heart health and fitness in women who have had early-stage breast cancer. It will enroll 100 survivors to see if the program helps their heart function, reduces body fat, and improves their q…

This study tests whether adding motivational counseling to a virtual exercise program helps cancer survivors stay physically active long-term. Researchers will compare two online programs over six months, tracking activity levels and quality of life. The goal is to help survivors…

This study is testing whether an online program called SCI&U, which connects people with recent spinal cord injuries to trained peer coaches, can help them better manage their health after leaving the hospital. Participants will have up to 14 online coaching sessions over 6 month…

This small pilot study aims to find out if different types of exercise are easy and enjoyable for women going through perimenopause. Researchers will compare standard aerobic exercise, high-intensity interval training (HIIT), and stretching over 6 weeks. The main goal is to see i…

This study is testing two ways to manage pain after repeat knee replacement surgery. It compares a standard method that includes a spinal morphine injection to a method that uses only targeted nerve blocks. The goal is to see if the nerve-block-only approach provides similar pain…

This study aims to validate a new, non-invasive breath test as a simpler way to measure how dietary protein helps build muscle. Researchers will compare results from this breath test against the current gold-standard method, which requires muscle biopsies. The goal is to make fut…

This study aims to understand how women's menstrual cycles and birth control pills affect how their bodies build muscle proteins after weight training. Researchers will measure protein building in muscle and throughout the body in 20 active women during different cycle phases. Th…

This study aims to understand how a common breast cancer hormone therapy affects heart and blood vessel health in the first six months of treatment. Researchers will compare 40 breast cancer patients starting this therapy to a similar group without cancer, measuring various heart…

This study aims to understand how the body processes an omega-3 supplement called EPA, turning it into another important fat called DHA. Researchers want to see if a person's biological sex or specific genes affect how quickly this conversion happens. Healthy participants will ta…

This study aims to understand how eating dairy products affects body weight, body fat, and metabolic health. Overweight teens (15-18) and older adults (60-80) will be randomly assigned to either eat three servings of dairy daily or keep their usual low-dairy diet for six months. …