University Of Toronto
Clinical trials sponsored by University Of Toronto, explained in plain language.
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Timing your meals may lower breast cancer risk, study finds
Prevention CompletedThis study looked at whether time-restricted eating (eating only during a set window each day) can lower biological and behavioral risk factors for breast cancer. It involved 178 women aged 50 or older with metabolic issues like prediabetes or type 2 diabetes. Participants follow…
Phase: NA • Sponsor: University of Toronto • Aim: Prevention
Last updated Jun 16, 2026 12:49 UTC
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Can a tiny electric zing prevent opioid breathing trouble?
Symptom relief CompletedAfter surgery, painkillers can slow breathing. This study tested a device that uses a mild electrical pulse on the skin to wake patients when their breathing stops for 10 seconds. Researchers enrolled 60 adults recovering from surgery to see if the system is practical and accepta…
Phase: NA • Sponsor: University of Toronto • Aim: Symptom relief
Last updated Jun 24, 2026 11:04 UTC
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Knee replacement patients may get better pain relief with a continuous nerve block
Symptom relief CompletedThis study tested whether a continuous nerve block using the drug ropivacaine can improve recovery after total knee replacement surgery. Sixty adults having knee replacement were given either the nerve block or a placebo. The goal was to see if the nerve block leads to better pai…
Phase: NA • Sponsor: University of Toronto • Aim: Symptom relief
Last updated Jun 22, 2026 11:57 UTC
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New hip block may keep leg strength while killing pain
Symptom relief CompletedThis study tested whether a low-concentration anesthetic injected near the hip can control pain after hip replacement surgery without weakening the leg muscles. Sixty adults having hip replacement received either a low or high concentration of the anesthetic. The goal was to see …
Phase: NA • Sponsor: University of Toronto • Aim: Symptom relief
Last updated Jun 10, 2026 13:26 UTC
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Could your gut bacteria be linked to anxiety? new study investigates
Knowledge-focused CompletedThis completed study from the University of Toronto looked at whether certain gut bacteria are linked to anxiety, depression, and panic disorders. 500 adults provided stool samples to test for H. pylori and other bacteria. The goal was to understand possible root causes, not to t…
Sponsor: University of Toronto • Aim: Knowledge-focused
Last updated Jun 25, 2026 04:39 UTC
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Same-Day consent for Low-Risk studies may be just as voluntary as earlier consent
Knowledge-focused CompletedThis study looked at whether patients feel pressured to join a low-risk anesthesia research study if asked on the day of surgery versus several days before. Researchers recruited 114 patients having day surgery and randomly invited them to a fake study either before or on the day…
Phase: NA • Sponsor: University of Toronto • Aim: Knowledge-focused
Last updated Jun 25, 2026 04:38 UTC
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COVID-19 vaccine study reveals immune response in people with HIV
Knowledge-focused CompletedThis study examined how the COVID-19 vaccine affects the immune system in people with HIV compared to those without HIV. Researchers followed 75 participants aged 55 and older for 48 weeks, taking blood and saliva samples. The goal was to understand vaccine effectiveness and any …
Sponsor: University of Toronto • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:05 UTC
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Algae oil study could shape future Omega-3 guidelines
Knowledge-focused CompletedThis study looked at how different doses of DHA (an omega-3 from algae oil) change EPA levels in the blood of 72 healthy vegetarians and vegans. Participants took one of six DHA doses daily for 8 weeks, and researchers tracked EPA changes using a carbon tracer. The goal is to hel…
Phase: PHASE1 • Sponsor: University of Toronto • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:48 UTC
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Can an app help your doctor know your family health risks?
Knowledge-focused CompletedThis study tested whether a family history app can help doctors collect and use information about patients' family health risks. Over 600 adults aged 30-69 took part. The goal was to see if the app leads to better screening and genetic referrals for conditions like cancer, heart …
Phase: NA • Sponsor: University of Toronto • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:06 UTC