Knee replacement patients may get faster recovery with continuous nerve block

NCT ID NCT05100706

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a continuous nerve block using the anesthetic ropivacaine can improve recovery after total knee replacement surgery. Sixty patients received either the active nerve block or a placebo. The goal was to see if the continuous block provides better pain relief and quality of recovery compared to a single shot.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ropivacaine

What this could lead to

If it works, this could provide better pain control and faster recovery for people undergoing knee replacement surgery.

What could go wrong

This is a small, early-stage study with only 60 participants, so results may not apply to everyone. The nerve block may not improve recovery significantly and carries risks like infection or nerve damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acute Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mount Sinai Hospital

    Toronto, Ontario, M5G 1X5, Canada