Knee surgery painkiller linked to catheter need – new trial seeks safer option

NCT ID NCT07050277

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study looks at whether skipping intrathecal morphine during knee revision surgery can lower the chance of needing a catheter for urinary retention. Fifty adults having non-infected knee revision will get either morphine or a placebo alongside standard nerve blocks. The goal is to see if pain control stays good while avoiding bladder complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mount Sinai Hospital

    RECRUITING

    Toronto, Ontario, M5G 1X5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Intrathecal morphine

What this could lead to

If successful, this could show that skipping intrathecal morphine during knee revision surgery lowers the risk of needing a catheter without worsening pain.

What could go wrong

This is a small, early-phase trial with only 50 participants, so results may not apply to everyone. The study is still recruiting, and the outcome is uncertain.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.