One shot or three? new study tests simpler knee pain treatment

NCT ID NCT07352540

First seen Feb 01, 2026 · Last updated May 08, 2026 · Updated 12 times

Summary

This study compares a single injection of hyaluronic acid to a series of three weekly injections for people with knee osteoarthritis. The goal is to see if the single shot works just as well for pain relief and knee function, while being more convenient. Forty-six adults with moderate to severe knee pain will be followed for 24 weeks.

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