University Of Erlangen-nürnberg Medical School

This study tests whether dapagliflozin, a drug used for diabetes and kidney protection, can improve kidney structure and blood flow in people who received a kidney transplant one year ago. About 48 participants will be randomly assigned to take dapagliflozin or standard care alon…

This study tests whether giving less radiation after surgery for certain head and neck cancers can reduce long-term side effects, like trouble swallowing, without allowing the cancer to come back. About 508 adults who have had surgery and need standard post-op radiation will be r…

This study tests a procedure called renal denervation, which uses ultrasound to calm overactive kidney nerves, in 12 dialysis patients with hard-to-treat high blood pressure. The goal is to see if it safely lowers blood pressure over 3 to 6 months. It is a small, early-stage tria…

This study tests two new imaging techniques—ultrasound localization microscopy and multispectral optoacoustic tomography—to check the health of kidney transplants without invasive procedures. Ten adult kidney transplant patients who already need a biopsy will also get these scans…

This study tests a new, high-resolution ultrasound technique called Ultrasound Localization Microscopy (ULM) to detect early kidney damage in children who have been treated for acute lymphoblastic leukemia (ALL). The method uses tiny bubbles (contrast agent) to see blood flow in …

This study tests a new ultrasound technique that uses a contrast dye and special computer processing to create detailed images of blood flow and tiny blood vessels in the kidneys. It will involve 20 children aged 1 month to 6 years with congenital kidney and urinary tract abnorma…

This study tests whether taking omega-3 fish oil capsules and doing simple resistance exercises with elastic bands can help cancer patients maintain muscle mass and strength. It involves 288 adults with various cancers who are at risk of muscle wasting. The goal is to improve phy…

This study looks at two different exercise programs—using flexi bands or whole-body electrical stimulation—for people with cancer. The goal is to see which one better helps maintain muscle strength, reduce inflammation, and improve quality of life during treatment. About 100 part…

This study creates a nationwide registry and biobank for children diagnosed with myeloproliferative neoplasms (MPNs)—rare blood cancers that cause overproduction of blood cells. By collecting medical data and blood samples from up to 500 children across Germany, researchers hope …

This study is for 300 people with salivary gland tumors (both cancerous and non-cancerous) to learn how the immune system reacts to these rare cancers. Researchers will collect tumor tissue and blood samples before and after treatment to find immune markers that might predict how…

This study is a registry that collects information from 100 people with advanced salivary gland cancer who receive radiation and chemotherapy together after surgery. The goal is to create a database to track how well the treatment works and its side effects. It is not testing a n…

This study is testing a new ultrasound method to look at tiny blood vessels in the kidneys of people with nephritis (kidney inflammation). Researchers will use contrast-enhanced ultrasound and ultrasound localization microscopy to create detailed images of kidney blood flow. The …

This study looks at immune markers in tumor tissue, saliva, stool, and blood from 250 head and neck cancer patients who cannot receive cisplatin chemotherapy. Researchers want to see if these markers can predict how well patients respond to chemoradiotherapy with docetaxel. The g…

This study uses a special eye scan called OCTA to measure the density of tiny blood vessels in the retina. Researchers will compare results from 64 people—half with cardiovascular disease and half healthy—to see if the scan can reliably detect vessel changes linked to heart probl…

This study looks at how the immune system changes in men with prostate cancer who receive brachytherapy (internal radiation). Researchers will collect blood and tissue samples before, during, and after treatment to track immune cells and DNA. The goal is to better understand the …

This observational study is collecting blood samples and medical images from 200 people with several types of solid tumors (like lung, head and neck, and esophageal cancers) who are receiving immunotherapy and radiation as part of their standard care. Researchers want to see if c…

This study tests whether 20 sessions of balance-challenge training on a stationary bike can improve safe cycling skills in adults aged 65 and older. Participants will be randomly assigned to the training or a control group, and their cycling ability will be measured on a test cou…