Can a diabetes drug shield transplanted kidneys?
NCT ID NCT06560801
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether dapagliflozin, a drug used for diabetes and kidney protection, can improve kidney structure and blood flow in people who received a kidney transplant one year ago. About 48 participants will be randomly assigned to take dapagliflozin or standard care alone. Researchers will examine kidney biopsies and MRI scans to look for changes in inflammation, scarring, and perfusion.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dapagliflozin (a diabetes drug that helps protect the kidneys)
What this could lead to
If it works, this could show that dapagliflozin helps preserve kidney health in transplant patients, potentially leading to better long-term outcomes.
What could go wrong
This is a small, early-phase study (48 people) looking at tissue changes, not hard outcomes like kidney failure. The drug may not show clear benefits or could cause side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Clinical Research Center (CRC)
RECRUITINGErlangen, Bavaria, 91054, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-••••