Microbubble ultrasound could catch kidney damage before It's too late

NCT ID NCT07313878

Recruiting now Diagnosis Sponsor: University of Erlangen-Nürnberg Medical School Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a new, high-resolution ultrasound technique called Ultrasound Localization Microscopy (ULM) to detect early kidney damage in children who have been treated for acute lymphoblastic leukemia (ALL). The method uses tiny bubbles (contrast agent) to see blood flow in the kidney's smallest vessels. Researchers hope it can find injury earlier than standard tests, allowing doctors to start protective treatments sooner. The study will enroll 30 children and teens who have completed or are undergoing ALL treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SonoVue (contrast agent for ultrasound)
What this could lead to: If successful, this could allow doctors to detect kidney damage from chemotherapy much earlier, enabling timely treatment to prevent long-term harm.
What could go wrong: This is a small pilot study with only 30 participants, so results may not apply to all patients. The technique is new and needs more testing before it can be widely used.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE LYMPHOBLASTIC LEUKAEMIAS (ALL) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE LYMPHOBLASTIC LEUKAEMIAS (ALL) LONG TERM FOLLOW-UP

Contacts and locations

Locations

Department of Pediatrics and Adolescent Medicine
RECRUITING

Erlangen, Baveria, 91054, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.