Microbubble ultrasound could catch kidney damage before It's too late

NCT ID NCT07313878

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a new, high-resolution ultrasound technique called Ultrasound Localization Microscopy (ULM) to detect early kidney damage in children who have been treated for acute lymphoblastic leukemia (ALL). The method uses tiny bubbles (contrast agent) to see blood flow in the kidney's smallest vessels. Researchers hope it can find injury earlier than standard tests, allowing doctors to start protective treatments sooner. The study will enroll 30 children and teens who have completed or are undergoing ALL treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SonoVue (contrast agent for ultrasound)

What this could lead to

If successful, this could allow doctors to detect kidney damage from chemotherapy much earlier, enabling timely treatment to prevent long-term harm.

What could go wrong

This is a small pilot study with only 30 participants, so results may not apply to all patients. The technique is new and needs more testing before it can be widely used.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Pediatrics and Adolescent Medicine

    RECRUITING

    Erlangen, Baveria, 91054, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact