15-Year watch begins for gene therapy recipients

NCT ID NCT06882317

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 40 people who previously received CLBR001, a gene-modified cell therapy, to monitor long-term safety over 15 years. No new treatment is given. Researchers will track side effects and check for any lingering virus from the gene therapy. The goal is to understand delayed risks, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
CLBR001 (a gene-modified immune cell therapy)
What this could lead to
If successful, this study will provide crucial safety data on gene-modified cell therapies, helping to guide future treatments.
What could go wrong
This is an observational follow-up study, not a treatment trial. It cannot prove the therapy works or is safe for new patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Indiana University Melvin and Bren Simon Comprehensive Cancer Center

    Indianapolis, Indiana, 46202, United States

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

  • Virtual Research Group- Premier Research

    Morrisville, North Carolina, 27560, United States

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