University Of Erlangen-nürnberg Medical School

This study tests whether giving less radiation after surgery for certain head and neck cancers can reduce long-term side effects like trouble swallowing, without increasing the chance of cancer coming back. About 508 adults who have had surgery and need standard post-operative ra…

This study tests a procedure called renal denervation, which uses ultrasound to calm overactive kidney nerves, in 12 adults with both end-stage kidney disease on dialysis and treatment-resistant hypertension. The goal is to see if it safely lowers 24-hour blood pressure. Particip…

This study tests if 20 sessions on a special stationary bike that wobbles unexpectedly can improve real-world cycling skills in adults aged 65 and older. Participants will be tested on a cycling course before and after training to see if they make fewer mistakes. The goal is to h…

This study looks at two different exercise programs—flexi band resistance training and whole-body electrical muscle stimulation—for people with cancer. The goal is to see which one better improves muscle strength, body composition, and quality of life. About 100 participants will…

This study tests whether a time-saving, joint-friendly muscle stimulation technology (whole-body electromyostimulation) can lower resting blood pressure and improve other heart-related risk factors in people with mild high blood pressure and overweight. Researchers will compare t…

This study looks at the immune system in people with salivary gland tumors to find markers that might predict how the disease will progress. Researchers will collect tumor tissue and blood samples from 300 participants before and after treatment. The goal is to better understand …

This study looks at 250 patients with head and neck cancers who cannot take the standard chemotherapy drug cisplatin. Researchers will analyze tumor tissue, saliva, stool, and blood samples to find biological markers that predict how well treatment with chemoradiotherapy and doce…

This study tests a new ultrasound technique called ULM to find early signs of kidney damage in children and teens who have been treated for acute lymphoblastic leukemia (ALL). About 30 survivors will be scanned to see if the method can detect problems before standard tests do. Th…

This study tests two new imaging methods—ultrasound and light-based scanning—to see if they can safely check the health of a kidney transplant. Ten adult kidney transplant patients who already need a biopsy will also get these non-invasive scans. If the scans work well, they migh…

This study looks at how the drug dapagliflozin affects the structure and blood flow of transplanted kidneys in people with reduced kidney function one year after transplant. About 48 participants will be randomly assigned to take dapagliflozin or not, and researchers will analyze…

This study uses a special, non-invasive eye scan called OCTA to look at tiny blood vessels in the back of the eye. Researchers want to see if these blood vessels look different in people with heart disease compared to healthy volunteers. The goal is to find a new, simple way to c…

This study creates a nationwide registry in Germany for children and teens diagnosed with myeloproliferative neoplasms (MPNs), a rare group of blood cancers. Researchers will collect medical data and blood samples from up to 500 participants to learn how these diseases differ in …

This study looks at how the immune system changes in 200 prostate cancer patients before, during, and after brachytherapy (internal radiation). Researchers will analyze blood and tissue samples to understand immune responses and track long-term outcomes like cancer recurrence and…

This study is collecting information from 100 people with advanced salivary gland cancer who receive standard radiation and chemotherapy after their tumor is removed. The goal is to create a database to better understand how well this treatment works and what side effects it caus…

This study tests a new, non-invasive ultrasound method to look at blood flow and tiny filters in the kidneys of children with congenital kidney and urinary tract problems (CAKUT). About 20 children aged 1 month to 6 years will participate. The goal is to see if this technique can…

This study aims to test a new, non-invasive ultrasound method to see and measure the tiny blood vessels in the kidneys of adults with proteinuria (protein in urine) or active urinary sediment. About 30 participants who already need a kidney biopsy will also get this special ultra…

This study is for people with certain advanced cancers (like lung, head and neck, or esophageal cancer) who are already scheduled to receive immunotherapy (PD-1/PD-L1 inhibitors). Researchers want to see if adding radiation therapy improves outcomes and, more importantly, if chan…