No needles, no naps: new nose scope could transform gut checks for Weight-Loss patients

NCT ID NCT06200961

Recruiting now Symptom relief Sponsor: Christopher C. Thompson, MD, MSc Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new, ultra-thin endoscope that goes through the nose without sedation, instead of the usual mouth-and-sedation approach. Researchers want to see if it improves patient experience and lowers costs for people in bariatric care. About 100 adults will try the device and report their satisfaction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Transnasal endoscopy (TNE) device
What this could lead to: If successful, this could make upper GI endoscopy safer, cheaper, and more accessible for people with obesity, without needing sedation.
What could go wrong: This is a small, early-stage study (100 participants) focused on patient experience, not on treating disease. The new scope may not be as effective or comfortable as standard sedated endoscopy.

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Conditions

The condition(s) this trial relates to.

Digestive System Diseases digestive system disorder morbid obesity Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROINTESTINAL DISEASES GI DISORDERS OBESE OBESITY OBESITY, MORBID

Contacts and locations

Locations

Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

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